Daniel José García Domínguez
Email: Solicitar correo
Perfil en ORCID: 0000-0001-8150-2747

Grupo de Investigación: Bioquimica Medica
Departamento/Unidad: Bioquímica Médica y Biología Molecular e Inmunología
Situación profesional: Plan Propio-Acceso

Participa en los siguientes proyectos/ayudas en la US:

• Proyecto de investigación:
  • Study of the prognostic and functional role of mesenchymal stem cell markers Endoglin and ALCAM in the disease progression of Clear cell sarcomas (CCS) and Desmoplastic small Round cell tumours (DSRCT) (P18-RT-735 - Equipo de Investigación)
  
  
• Ayuda a la investigación:
  • Incentivo al Grupo de Investigación CTS-035 (2017/CTS-035 - Investigador)
  
  

Cobertura de la base de datos de proyectos, véase aqui

Publicaciones:

Publicaciones en Revistas

García, Daniel José, Hontecillas, Lourdes, Palazón , Natalia, Jiménez Cortegana, Carlos, Sánchez Margalet, Victor, et. al.:
Review/Reseña: Tumor Immune Microenvironment in Lymphoma: Focus on Epigenetics. En: Cancers. 2022. Vol. 14. Núm. 6

García, Daniel José:
Treatment-driven selection of chemoresistant Ewing sarcoma tumors with limited drug distribution. En: Journal of controlled release. 2020. https://doi.org/10.1016/j.jconrel.2020.05.032

García, Daniel José, Hontecillas, Lourdes:
RING1B recruits EWSR1-FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis. En: Science Advances. 2020. 10.1126/sciadv.aba3058

García, Daniel José, Hontecillas, Lourdes, Morón Civanto, Francisco Jesús, De Álava, Enrique:
An Inducible Ectopic Expression System of EWSR1-FLI1 as a Tool for Understanding Ewing Sarcoma Oncogenesis. En: PLoS One. 2020. Vol. 15. Núm. 6. 10.1371

Hontecillas, Lourdes, García, Daniel José, García Mejías, Rosa María, Ramirez Villar, Gema Lucia, Saez Torres, Carmen, et. al.:
HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients. En: Oncotarget. 2017. Vol. 8. Núm. 70. Pag. 115290-115303. 10.18632/oncotarget.23256

Hontecillas Prieto, Lourdes, García, Daniel José, Pascual Vaca, Diego Pascual Vaca, Garcia Mejias, Rosa, Marcilla, David, et. al.:
Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients. En: Oncotarget. 2017. 10.18632/oncotarget.14491

Madoz Gúrpide, Juan, Hontecillas, Lourdes, García, Daniel José, Monteiro, Ana, De Álava, Enrique:
Proteomic Profiling of Ewing Sarcoma Reveals a Role for TRAF6 in Proliferation and Ribonucleoproteins/RNA Processing. En: Journal of Proteomics and Bioinformatics. 2016

Hernandez Muñoz, I, García, Daniel José, Hontecillas, Lourdes, De Álava, Enrique, Mora, J:
RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-¿B pathway, independently of the fusion oncoprotein. En: Oncotarget. 2016. RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-¿B pathway, independently of the fusion oncoprotein

Monteiro, Ana, García, Daniel José:
Review/Reseña: Innovative therapies in Ewing sarcoma. En: Advances in Anatomic Pathology. 2014

Mackintosh, Carlos, García, Daniel José, Odoñez, Jose Luis, Ginel Picardo, Alicia, De Álava, Enrique:
WEE1 accumulation and deregulation of S-phase proteins mediate MLN4924 potent inhibitory effect on Ewing sarcoma cells. En: Oncogene. 2013

Mackintos, Carlos, Ordoñez, Jose Luis, García, Daniel José, Sevillano , Victoria, Scotlandi, Katia, et. al.:
1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma. En: Oncogene. 2012

García, Daniel José, Frade López, Jose María:
Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis. En: Molecular Biology of the Cell. 2011. 10.1091/mbc.E10-10-0808

García, Daniel José, Monteiro, Ana, Barbado González, Mª Victoria, Barbado González, Mª Victoria:
Review/Reseña: "The clinical relevance of molecular genetics in soft tissue sarcomas". En: Advances in Anatomic Pathology. 2010. Vol. 17. Pag. 162-181. DOI: 10.1097/PAP.0b013e3181d98cbf

García, Daniel José:
Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis. 10.1091/mbc.E10-10-0808

Aportaciones a Congresos

Hontecillas, Lourdes, García, Daniel José, Rodríguez, Pablo, García Mejías, Rosa María, Pascual Pastó, Guillem, et. al.:
Combination of epigeneic drugs (SAHA-HCI2509) synergistically affects proliferation in Ewing Sarcoma. Poster en Congreso. Connective Tissue Oncology Society 2016 Annual Meeting. Lisboa, Portugal. 2016

García, Daniel José, Hontecillas, Lourdes, Rodríguez, Pablo, García Mejías, Rosa María, Diaz Martin, Juan, et. al.:
Preclinical Study of the Combination of Pevonedistat With Doxorubicin, Gemcitabine or Bmn673 in Ewing Sarcoma. Poster en Congreso. CTOS 2016 Annual meeting. , - Lisboa, Portugal. 2016

Rodríguez, Pablo, Romero Pérez, Laura, García Mejías, Rosa María, García, Daniel José, Monteiro, Ana, et. al.:
Deregulation of Hippo Tumor Supressor Pathway in Ewing Sarcoma. Poster en Congreso. Deregulation of Hippo Tumor Supressor Pathway in Ewing Sarcoma. , - Lisboa, Portugal, Portugal. 2016

García, Daniel José, De Álava, Enrique:
Relevance of Copy Number Alterations in Ewing Sarcoma: Gain of 1q Defines a Subset of Patients With Worse Outcome, Probably Caused by Dtl/Cdt2 Overexpression and Subsequent Cell Cycle Deregulation. Poster en Congreso. 21st Meeting of the European Association for Cancer Research (Eacr). Noruega. 2010

Patentes:

García, Daniel José, De Álava, Enrique:
Methods of Prognosticating and Treating Ewing Sarcoma/Pnet and Other Neoplasms. Patente de invención, Propiedad industrial. Solicitud: 2010-06-23