Veit Goder
Telefono: 954556230
Email: Solicitar correo
Página personal: http://personal.us.es/vgoder
Perfil en ORCID: 0000-0003-0854-4873
Perfil en WOS: F-8092-2016

Grupo de Investigación: Expresion Genica en Eucariontes
Departamento/Unidad: Genética
Situación profesional: Profesor Titular de Universidad

Responsable de los siguientes proyectos/ayudas en la US:

• Proyecto de investigación:
  • Análisis de nuevos mecanismos celulares en ERAD y microautofagia (PID2022-136665NB-I00)
  • Mecanismos Moleculares Relacionados con el Control de la Calidad y la Degradación Post-ER de las Proteínas (PID2019-108564GB-I00)
  • Funciones del Retículo Endoplasmático en la Homeostasis Celular (BFU2016-78265-P)
  • Conexión Entre Erad y Fusión de Membranas (BFU2009-07290)
  
  

Participa en los siguientes proyectos/ayudas en la US:

• Proyecto de investigación:
  • A New Look at the Functional Organization of the Secretory Pathway (P20_01240 - Equipo de Investigación)
  • Regulación de la Organización Funcional de la Ruta Secretora Temprana: Papel Activo de las Proteínas Cargo y los Receptores de Transporte (BFU2014-59309-P - Equipo Trabajo (Solicitud))
  • Mecanismos Moleculares del Control de Calidad de las Proteínas Ancladas a GPI en el Retículo Endoplasmico. Implicaciones en el Control Inmune en Cáncer y Enfermedades Infecciosas. (P09-CVI-4503 - Investigador)
  
  
• Ayuda a la investigación:
  • Incentivo al Grupo de Investigación BIO-271 (2017/BIO-271 - Investigador)
  • Incentivo al Grupo de Investigación BIO-271 (2011/BIO-271 - Investigador)
  • Incentivo al Grupo de Investigación BIO-271 (2010/BIO-271 - Investigador)
  • Ayuda a la Consolidación del Grupo de Investigación BIO-271 (2009/BIO-271 - Investigador)
  
  

Cobertura de la base de datos de proyectos, véase aqui

Publicaciones:

Capítulos en Libros

Goder, Veit, Spiess, Martin:
Topogenesis of Membrane Proteins. Pag. 2561-2567. En: Encyclopedia of Molecular Biology.. Nueva York, EE.UU. John Wiley & Sons Ltd. 1999

Publicaciones en Revistas

Lemus, Leticia, Goder, Veit:
Nature reviews. Molecular cell biology. En: Nature Reviews. Molecular Cell Biology. 2023. https://doi.org/10.1038/s41580-023-00616-9

Lemus, Leticia, Goder, Veit:
Pep4-dependent microautophagy is required for post-ER degradation of GPI-anchored proteins. En: Autophagy. 2022. Vol. 18. Núm. 1. Pag. 223-225. 10.1080/15548627.2021.1971929

Lemus, Leticia, Matic, Zrinka, Gal, Lihi, Schuldiner, Maya, Goder, Veit:
Post-ER degradation of misfolded GPI-anchored proteins is linked with microautophagy. En: Current Biology. 2021. Vol. 31. Núm. 18. Pag. 4025-4037. 10.1016/j.cub.2021.06.078

Klionsky, Daniel, Ruano, Diego, Sánchez Vera, Victoria, Argúelles Castilla, Sandro, Pérez Lara , Ángel, et. al.:
Review/Reseña: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). En: Autophagy. 2021. Vol. 17. Núm. 1. Pag. 1-382. 10.1080/15548627.2020.1797280

Goder, Veit, Alanis Dominguez, Enrique, Bustamante, Mar:
Review/Reseña: Lipids and their (un)known effects on ER-associated protein degradation (ERAD). En: Biochimica et Biophysica Acta (BBA): Molecular and Cell Biology of Lipids. 2020. Vol. 1865. Núm. 1. 10.1016/j.bbalip.2019.06.014

Lopez Sergio, Pérez Linero, Ana María, Manzano López, Javier, Sabido, Susana, Cortes Gomez, Alejandro, et. al.:
Dual Independent Roles of the p24 Complex in Selectivity of Secretory Cargo Export From the Endoplasmic Reticulum. En: Cells. 2020. 10.3390/cells9051295

Lemus, Leticia, Matic, Zrinka, Goder, Veit:
Articulo en prensa: A post-ER degradation pathway that relies on protease-dependent internalization from the vacuolar membrane. DOI: 10.1101/778530. 2019. doi: https://doi.org/10.1101/778530. FIRST AUTHOR

Guerrero Gómez, David, Mora Lorca, Jose Antonio, Sáenz Narciso, Beatriz, Naranjo Galindo, Francisco José, Parrado Fernandez, Cristina, et. al.:
Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation. En: Cell Death and Differentiation. 2019. Vol. 26. Núm. 9. Pag. 1545-1565. 10.1038/s41418-018-0270-9

Sabido, Susana, Pérez Linero, Ana María, Rodríguez, Sofía de la Oliva, Manzano López, Javier, Goder, Veit, et. al.:
Meeting-Abstract: Multireceptor complexes regulate cis-Golgi assembly by facilitating vesicle tethering. En: FEBS OPEN Bio. 2018. Vol. 8

Goder, Veit:
Specific COPII vesicles transport ER membranes to sites of autophagosome formation. En: Molecular and Cellular Oncology. 2017. Vol. 4. Núm. 1. 0.1080/23723556.2016.1173768

Sikorska, Natalia, Lemus, Leticia, Aguilera Romero, Maria Auxiliadora, Manzano López, Javier, Riezman, Howard, et. al.:
Co-FIRST AUTHOR. Cuartil Q1. IF: 7.955. Limited ER quality control for GPI-anchored proteins. DOI: 10.1083/jcb.201602010. En: Journal of Cell Biology. 2016. Vol. 213. Núm. 6. Pag. 693-704. 10.1083/jcb.201602010

Lemus, Leticia, Goder, Veit:
Cuartil Q1. IF: 8.593. A SNARE and specific COPII requirements define ER-derived vesicles for the biogenesis of autophagosomes. DOI: 10.1080/15548627.2016.1164368. En: Autophagy. 2016. Vol. 12. Núm. 6. Pag. 1049-1050. 10.1080/15548627.2016.1164368

Lemus, Leticia, Ribas Salgueiro, Juan Luis, Sikorska, Natalia, Goder, Veit:
FIRST AUTHOR. Cuartil Q1. IF: 8.282. An ER-Localized SNARE Protein Is Exported in Specific COPII Vesicles for Autophagosome Biogenesis. DOI: 10.1016/j.celrep.2016.01.047. En: Cell Reports. 2016. Vol. 14. Núm. 7. Pag. 1710-1722. 10.1016/j.celrep.2016.01.047

Manzano López, Javier, Pérez Linero, Ana María, Aguilera Romero, Maria Auxiliadora, Martín Rubio, María Esther, Okano, Tatsuki, et. al.:
COPII coat composition is actively regulated by luminal cargo maturation. En: Current Biology. 2015. Vol. 25. Núm. 2. Pag. 152-162. 10.1016/j.cub.2014.11.039

Lemus, Leticia, Goder, Veit:
Review/Reseña: Cuartil Q1. IF: 4.829. Regulation of Endoplasmic Reticulum-Associated Protein Degradation (ERAD) by Ubiquitin. DOI: 10.3390/cells3030824. En: Cells. 2014. Vol. 3. Núm. 3. Pag. 824-847. 10.3390/cells3030824

Manzano López, Javier, Aguilera Romero, Maria Auxiliadora, Pérez Linero, Ana María, Sánchez García, Manuel Alejandro, Martín Rubio, María Esther, et. al.:
Meeting-Abstract: Ted1p monitors GPI lipid remodeling and coordinates this with the er exit of GPI-anchored proteins driven by the p24 complex. En: The FEBS Journal. 2012. Vol. 279. Pag. 544-545

Goder, Veit:
Review/Reseña: Roles of ubiquitin in Endoplasmic Reticulum-Associated Protein Degradation (ERAD). En: Current Protein & Peptide Science. 2012. Vol. 13. Núm. 5. Pag. 425-435. 10.2174/138920312802430572

Goder, Veit, Melero, Alejandro:
Protein o-Mannosyltransferases Participate in ER Protein Quality Control. En: Journal of Cell Science. 2011. Pag. 144-153

Goder, Veit, Carvalho, Pedro, Rapoport, Tom A.:
The ER-Associated Degradation Component Der1p and Its Homolog Dfm1p Are Contained in Complexes With Distinct Cofactors of the Atpase Cdc48p. En: FEBS Letters. 2008. Vol. 582. Núm. 11. Pag. 1575-1580

Junne, Tina, Schwede, Torsten, Goder, Veit, Spiess, Martin:
Mutations in the Sec61p Channel Affecting Signal Sequence Recognition and Membrane Protein Topology. En: Journal of Biological Chemistry. 2007. Vol. 282. Núm. 45. Pag. 33201-33209

Carvalho, Pedro, Goder, Veit, Rapoport, Tom A.:
Distinct Ubiquitin-Ligase Complexes Define Convergent Pathways for the Degradation of ER Proteins. En: Cell. 2006. Vol. 126. Núm. 2. Pag. 361-373

Junne, Tina, Schwede, Torsten, Goder, Veit, Spiess, Martin:
The Plug Domain of Yeast Sec61p is Important for Efficient Protein Translocation, But is Not Essential for Cell Viability. En: Molecular Biology of the Cell. 2006. Vol. 17. Núm. 9. Pag. 4063-4068. 10.1091/mbc.E06-03-0200

Goder, Veit, Junne, Tina, Spiess, Martin:
Sec61p Contributes to Signal Sequence Orientation According to the Positive-Inside Rule. En: Molecular Biology of the Cell. 2004. Vol. 15. Núm. 3. Pag. 1470-1478

Rapoport, Tom A., Goder, Veit, Heinrich, Sven U., Matlack, Kent:
Review/Reseña: Membrane-Protein Integration and the Role of the Translocation Channel. En: Trends in Cell Biology. 2004. Vol. 14. Núm. 10. Pag. 568-575

Goder, Veit, Spiess, Martin:
Molecular Mechanism of Signal Sequence Orientation in the Endoplasmic Reticulum. En: EMBO Journal. 2003. Vol. 22. Núm. 14. Pag. 3645-3653

Goder, Veit, Spiess, Martin:
Review/Reseña: Topogenesis of Membrane Proteins: Determinants and Dynamics. En: FEBS Letters. 2001. Vol. 504. Núm. 3. Pag. 87-93

Roesch, Karin, Naeher, Dieter, Laird, Vivienne, Goder, Veit, Spiess, Martin:
The Topogenic Contribution of Uncharged Amino Acids on Signal Sequence Orientation in the Endoplasmic Reticulum. En: Journal of Biological Chemistry. 2000. Vol. 275. Núm. 20. Pag. 14916-14922

Goder, Veit, Crottet, Pascal, Spiess, Martin:
In Vivo Kinetics of Protein Targeting to the Endoplasmic Reticulum Determined by Site-Specific Phosphorylation. En: EMBO Journal. 2000. Vol. 19. Núm. 24. Pag. 6704-6712

Goder, Veit, Bieri, Christoph, Spiess, Martin:
Glycosylation Can Influence Topogenesis of Membrane Proteins and Reveals Dynamic Reorientation of Nascent Polypeptides Within the Translocon. En: Journal of Cell Biology. 1999. Vol. 147. Núm. 2. Pag. 257-266

Goder, Veit, Beckert, Vita, Pfeil, Wolfgang, Bernhardt, Rita:
Impact of the Presequence of a Mitochondrium-Targeted Precursor, Preadrenodoxin, on Folding, Catalytic Activity, and Stability of the Protein in Vitro. En: Biochemistry. 1998. Vol. 359. Núm. 1. Pag. 31-41

Aportaciones a Congresos

Lemus, Leticia, Goder, Veit:
Post-ER degradation of misfolded GPI-anchored proteins is linked with microautophagy. Poster en Congreso. The Endoplasmic Reticulum (ER) Conference: Structure, Function, and Disease. Virtual. International. 2021

Lemus, Leticia, Matic, Zrinka, Fadel, Amir, Gal, Lihi, Schuldiner, Maya, et. al.:
A post-ER degradation pathway that relies on protease-dependent internalization from the vacuolar membrane. Ponencia en Congreso. A post-ER degradation pathway that depends on noncanonical internalization from the vacuolar membrane. BEST POSTER PRIZE. Cáceres, España. 2020

Lemus, Leticia, Matic, Zrinka, Fadel, Amir, Gal, Lihi, Schuldiner, Maya, et. al.:
A post-ER degradation pathway that relies on protease-dependent internalization from the vacuolar membrane. Ponencia en Congreso. A post-ER degradation pathway that relies on protease-dependent internalization from the vacuolar membrane. AWARDED BEST POSTER PRIZE. Cáceres, España. 2020

Lemus, Leticia, Matic, Zrinka, Goder, Veit:
A cellular post-ER degradation pathway that depends on non-canonical internalization from the vacuolar membrane. AWARDED: BEST POSTER PRESENTATION. Poster en Congreso. A cellular post-ER degradation pathway that depends on non-canonical internalization from the vacuolar membrane. Ericeira, Lisboa, Portugal. 2019

Guerrero Gómez, David, Mora Lorca, Jose Antonio, Saenz Narciso, Beatriz, Naranjo Galindo, Francisco José, Muñoz Lobato, Fernando, et. al.:
Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation. Comunicación en congreso. VII Spanish C. elegans Meetin. . Barcelona. 2019

Sabido, Susana, Pérez Linero, Ana María, Rodríguez, Sofía de la Oliva, Manzano López, Javier, Goder, Veit, et. al.:
Multireceptor complexes regulate cis-Golgi assembly by facilitating vesicle fusion. Poster en Congreso. The 43rd FEBS congress. Praga, - Praga, República Checa. 2018

Lemus, Leticia, Velardo, Andrea, Goder, Veit:
Involvement of the phospholipase Atg15 in the turnover of the misfolded GPI-anchored protein Gas1* in yeast. Poster en Congreso. Involvement of the phospholipase Atg15 in the turnover of the misfolded GPI-anchored protein Gas1* in yeast. Miraflores de la Sierra. Madrid. España. 2018

Rodríguez, Ana, Lemus, Leticia, Goder, Veit:
ERAD is sensitive to M phase checkpoint aberration. Poster en Congreso. ERAD is sensitive to M phase checkpoint aberration. Lucca, Italy. 2018

Lemus, Leticia, Goder, Veit:
Post-ER Quality Control of GPI-APs. Ponencia en Congreso. Post-ER Quality Control of GPI-APs. Post-ER Quality Control of GPI-APs. La Antilla, Huelva. 2018

Lemus, Leticia, Goder, Veit:
Connections between Autophagy and ER quality control. India. EMBO Symposium Autophagy: Cellular mechanisms and significance in health and disease. INTERNACIONAL. Lugar: Bhubaneswar, India. Poster en Congreso. Connections between Autophagy and ER quality control. Bhubaneswar, India. 2017

Lemus, Leticia, Goder, Veit:
Connections of SNAREs and Cdc48 in autophagosome biogenesis. 2nd NEAR meeting AUTOFAGIA. Miraflores, España. INTERNACIONAL. Ponencia en Congreso. Connections of SNAREs and Cdc48 in autophagosome biogenesis. Miraflores, España. 2017

Lemus, Leticia, Goder, Veit:
Interplay between ERAD and Autophagy: an ultrastructural approach. Miraflores, Madrid, España. INTERNACIONAL. PONENCIA. Ponencia en Congreso. Interplay between ERAD and Autophagy: an ultrastructural approach. Miraflores, Madrid, España. 2016

Sikorska, Natalia, Lemus, Leticia, Aguilera Romero, Maria Auxiliadora, Manzano López, Javier, Riezman, Howard, et. al.:
Limited ER quality control for GPI-anchored proteins. Connections of SNAREs and Cdc48 in autophagosome biogenesis. INTERNACIONAL. Ponencia en Congreso. EMBO Conference: Structure and function of the endoplasmic reticulum. Girona, Spain. 2016

Goder, Veit, Lemus, Leticia:
Specific COPII-dependent vesicles transport ER membranes and SNARE proteins to sites of autophagosome formation. Ponencia en Congreso. 4th Meeting of the Spanish Autophagy Group, 1st NEAR meeting. Miraflores, Spain. 2016

Lemus, Leticia, Goder, Veit:
Interplay between ERAD and autophagy-an ultrastructural approach. POSTER PRESENTATION. INTERNACIONAL. EMBL, Heidelberg, Germany.. Poster en Congreso. Interplay between ERAD and autophagy-an ultrastructural approach. EMBL, Heidelberg, Germany. 2016

Manzano López, Javier, Pérez Linero, Ana María, Aguilera Romero, Maria Auxiliadora, Martín Rubio, María Esther, Okano, Tatsuki, et. al.:
COPII coat composition is actively regulated by luminal cargo maturation. Poster en Congreso. XVI Congreso Sociedad Española de Biología Celular (SEBC). Sevilla. 2015

Lemus, Leticia, Goder, Veit:
Interplay between ERAD and autophagy. Ponencia en Congreso. 3rd Meeting of the Spanish Autophagy Group. Seville, Spain. 2015

Lemus, Leticia, Ribas Salgueiro, Juan Luis, Sikorska, Natalia, Goder, Veit:
Novel membrane carriers from the Endoplasmic Reticulum contribute to autophagosome biogenesis. INTERNACIONAL. Ponencia en Congreso. EMBO Conference: The Endoplasmic Reticulum (ER) as a hub for organelle communication. Girona, Spain. 2014

Goder, Veit, Lemus, Leticia:
Relocation of an ER-resident SNARE protein for membrane fusions during autophagosome biogenesis. Ponencia en Congreso. Joint Meeting of Nordic, Spanish and French Autophagy Networks. Toulouse, France. 2014

Lemus, Leticia, Ribas Salgueiro, Juan Luis, Sikorska, Natalia, Goder, Veit:
Conditional routing of an ER-resident SNARE protein to autophagosomes for fusion with the vacuole. AWARDED: BEST POSTER PRIZE. Poster en Congreso. Gordon Research Conference on: Autophagy in Stress, Development & Disease. Renaissance Tuscany Il Ciocco Resort, Lucca (Barga), Italy. 2014

Manzano López, Javier, Aguilera Romero, Maria Auxiliadora, Pérez Linero, Ana María, Martín Rubio, María Esther, Wellinger, Ralf Erik, et. al.:
The p24 complex uses a lectin-based mechanism to link GPI-anchored proteins to specific COPII proteins. Poster en Congreso. XV Congreso de la Sociedad Española de Biología Celular. - Madrid, España. 2013

Goder, Veit:
Macroautophagy requires a specific endoplasmic reticulum fusion machinery. Ponencia en Congreso. V.Meeting of the Spanish Network on Functional integration of membrane trafficking, intracellular signaling and cytoskeleton dynamic. Barcelona, Spain. 2012

Rodriguez, Ana, Goder, Veit:
A Yeast-Based Screen to Identify Cellular Components Involved in Erad of GPI-Anchored Proteins Type of Presentation: Poster en Congreso. EMBO Conference: The physiology of the endoplasmic reticulum (ER): Function and dysfunction. Girona, Spain. 2012

Sikorska, Natalia, Goder, Veit:
Macroautophagy in S.cerevisiae requires a specific endoplasmic reticulum fusion machinery. Poster en Congreso. EMBO Conference: The physiology of the endoplasmic reticulum (ER): Function and dysfunction. Girona, Spain. 2012

Pérez Linero, Ana María, Manzano López, Javier, Sánchez García, Manuel Alejandro, Martín Rubio, María Esther, Goder, Veit, et. al.:
The functional structure of ER Exit Sites and early Golgi requires cooperation between Erv14p and p24 complex cargo receptors. Poster en Congreso. 22nd IUBMB & 37th FEBS Congress. From Single Molecules to Systems Biology. Seville, Spain. 2012

Manzano López, Javier, Aguilera Romero, Maria Auxiliadora, Pérez Linero, Ana María, Sánchez García, Manuel Alejandro, Martín Rubio, María Esther, et. al.:
Ted1p monitors GPI lipid remodeling and coordinates this with the ER exit of GPI-anchored proteins driven by the p24 complex. Poster en Congreso. 22nd IUBMB & 37th FEBS Congress. From Single Molecules to Systems Biology. Seville, Spain. 2012

Manzano López, Javier, Aguilera Romero, Maria Auxiliadora, Pérez Linero, Ana María, Sánchez García, Manuel Alejandro, Goder, Veit, et. al.:
Ted1p monitors GPI lipid remodeling and coordinates this with the COPII-cargo adaptor function of the p24 complex. Poster en Congreso. The Physiology of the Endoplasmic Reticulum: Function and Dysfunction. Girona (Spain). 2012

Pérez Linero, Ana María, Manzano López, Javier, Goder, Veit, Muñiz Guinea, Manuel:
The functional structure of ER exit sites and early Golgi requires cooperation between Erv14p and p24 complex cargo receptors. Poster en Congreso. XIV Congress of the Spanish Society for Cell Biology (SEBC). Málaga, España. 2011

Rodriguez, Ana, Goder, Veit:
A Yeast-Based Screen to Identify Cellular Components Involved in Erad of GPI-Anchored Proteins. Poster en Congreso. XIV Congreso de la Sociedad Espanola de Biologia Celular. Malaga, Spain. 2011

Goder, Veit:
Protein O-mannosyltransferases participate in ER protein quality control. Ponencia en Congreso. International EMBO Conference: Towards a comprehensive understanding of endoplasmic reticulum functions. Girona, Spain. 2010

Goder, Veit, Rapoport, Tom A.:
Molecular Machineries involved in endoplasmic reticulum associated protein degradation (ERAD). Poster en Congreso. International Symposium ¿Protein Sorting¿. Freiburg, Germany. 2005

Goder, Veit, Spiess, Martin:
Molecular mechanism of signal sequence orientation in the endoplasmic reticulum. Poster en Congreso. International Symposium: Protein and Membrane Transport in the Secretory Pathway. Göttingen, Germany. 2002

Goder, Veit, Spiess, Martin:
Molecular mechanism of signal sequence orientation in the endoplasmic reticulum. Poster en Congreso. International Conference ¿Sequence, Structure and Function of Membrane Protein Systems. Zichron Ya¿ocov, Israel. 2001

Goder, Veit:
Site-specific phosphorylation used as a marker for membrane protein topology and as a timer to estimate protein targeting to the ER. Ponencia en Congreso. Macromolecular Transport Across Cellular Membranes. Georgia, Savannah, USA. 2000

Goder, Veit, Bieri, Christoph, Spiess, Martin:
Dynamic topogenesis of membrane proteins. Poster en Congreso. 2nd International Cell Biology Symposium of the MDC:¿ Protein Transport and Stability¿. Max-Delbruck-Centrum, Berlin-Buch, Berlin, Germany. 1998

Goder, Veit, Beckert, Vita, Bernhardt, Rita:
Electron transfer properties of preadrenodoxin. Poster en Congreso. 9th International Conference on Cytochrome P450: Biochemistry, Biophysics and Molecular Biology. Zurich, Switzerland. 1995

Tesis dirigidas y co-dirigidas:

Lemus, Leticia:
Interplay between the endoplasmic reticulum and cellular homeostasis. Trabajo de la Tesis fue publicada en revistas de gran prestigio Internacinal. Tesis Doctoral. 2017

(Doctorando no grabado)
Interplay between the endoplasmic reticulum and cellular homeostasis. Tesis Doctoral. 2017

(Doctorando no grabado)
Interplay between the endoplasmic reticulum and cellular homeostasis. Tesis Doctoral. 2017