David Rodríguez Lucena
Telefono: 954 55 71 50 / 51517
Email: Solicitar correo
Página personal: https://prisma.us.es/investigador/9507
Perfil en ORCID: 0000-0001-5308-3979

Grupo de Investigación: Quimica Farmaceutica Aplicada
Departamento/Unidad: Química Orgánica y Farmacéutica
Situación profesional: Profesor Permanente Laboral - Mod. PCD

Participa en los siguientes proyectos/ayudas en la US:

• Proyecto I+D+i:
  • Preparación, análisis y evaluación de oligosacáridos prebióticos derivados de sacarosa, fructosa y lactosa (P06-AGR-02150 - Otro Investigador)
  • Glicomiméticos mono y ologosacarídicos y estudio de sus interacciones con biomoléculas (CTQ2004-05854 - Becario)
  
  
• Ayuda a la investigación:
  • Incentivo al Grupo de Investigación FQM-308 (2017/FQM-308 - Investigador)
  • Incentivo al Grupo de Investigación FQM-308 (2011/FQM-308 - Investigador)
  • Incentivo al Grupo de Investigación FQM-308 (2010/FQM-308 - Investigador)
  • Ayuda a la Consolidación del Grupo de Investigación FQM-308 (2009/FQM-308 - Investigador)
  • Ayuda a la Consolidación del Grupo de Investigación FQM-308 (2008/FQM-308 - Investigador)
  • Ayuda a la Consolidación del Grupo de Investigación FQM-308 (2007/FQM-308 - Investigador)
  • Ayuda a la Consolidación del Grupo de Investigación FQM-308 (2005/FQM-308 - Investigador)
  
  

Cobertura de la base de datos de proyectos, véase aqui

Publicaciones:

Publicaciones en Revistas

Delgado Pujol, Ernesto Javier, Martinez , Guillermo, Casado, David, Vázquez Cabello, Juan, León, Jesús, et. al.:
Review/Reseña: Hydrogels and Nanogels: Pioneering the Future of Advanced Drug Delivery Systems. En: Pharmaceutics. 2025. Vol. 17. Núm. 2. 10.3390/pharmaceutics17020215

García, Francisco Javier, Rodríguez Lucena, David, Romero, Juan Jesús, Hamad Gómez, Said, Carrillo Carrión, Carolina, et. al.:
Exploiting Cross-Responsiveness of Fluorescent Interpenetrated Zirconium¿Organic Frameworks Integrated in Polymeric Membranes as a Multi-Analyte Gas Sensor Array. En: Advanced Optical Materilas. 2024. Vol. 12. Núm. 30. 10.1002/adom.202401081

García, Francisco Javier, Romero, Juan Jesús, Rodríguez Lucena, David, Pedrosa Poyato, Jose Maria, Carrillo Carrión, Carolina:
Nanosized Porphyrinic Metal-Organic Frameworks for the Construction of Transparent Membranes as a Multiresponsive Optical Gas Sensor. 2024. Vol. 4. Núm. 10. 10.1002/smsc.202400210

Lebrón Romero, José Antonio, Ostos Marcos, Francisco José, Martínez Santa, Marta, García, Francisco Javier, Lopez Lopez, Manuel, et. al.:
Biocompatible metal-organic frameworks as promising platforms to eradicate HIV reservoirs ex vivo in people living with HIV. En: Journal of Materials Chemistry B. 2024. Vol. 12. Pag. 5220-5237. 10.1039/D4tb00272e

Compain, Philippe, Decroocq, Camille, Joosten, Antoine, De Sousa, Julien, Rodríguez Lucena, David, et. al.:
Rescue of Functional CFTR Channels in Cystic Fibrosis: A Dramatic Multivalent Effect Using Iminosugar Cluster-Based Correctors. En: ChemBioChem. 2013. Vol. 14. Pag. 2050-2058. 10.1002/cbic.201300312

Decroocq, Camille, Rodríguez Lucena, David, Ikeda, Kyoko, Asano, Naoki, Compain, Philippe:
Cyclodextrin-Based Iminosugar Click Clusters: The First Examples of Multivalent Pharmacological Chaperones for the Treatment of Lysosomal Storage Disorders. En: ChemBioChem. 2012. Vol. 13. Pag. 661-664. 10.1002/cbic.201200005

Decroocq, Camille, Mamani Laparra, Laura, Rodríguez Lucena, David, Compain, Philippe:
Synthesis of Azide-armed ¿-1-C-Alkylimino- d-xylitol Derivatives as Key Building Blocks for the Preparation of Iminosugar Click Conjugates. En: Journal of Carbohydrate Chemistry. 2011. Vol. 30. Pag. 559-574. 10.1080/07328303.2011.610544

Rodríguez Lucena, David, Morin, Marie S.t., Compain, Philippe:
Concise Synthesis of Bicyclic Aminals by Way of Catalytic Intramolecular C-H Amination and Evaluation of Their Reactivity as Iminium Precursors. En: Letters in Organic Chemistry. 2011. Vol. 8. Núm. 3. Pag. 155-162

Gramage Doria, Rafael, Rodríguez Lucena, David, Armspach, Dominique, Egloff, Coraline, Jouffroy, Matthieu, et. al.:
Regioselective Double Capping of Cyclodextrin Scaffolds. En: Chemistry: A European Journal. 2011. Vol. 17. Pag. 3911-3921. 10.1002/chem.201002541

Rodríguez Lucena, David, Schalk, Isabelle J., Mislin, Gaetan L.a.:
Synthesis of gemini triethylene-tetramine bridged bis-tridentate iron(III) chelators. En: Tetrahedron. 2011. Vol. 67. Pag. 2149-2154

Decroocq, Camille, Rodríguez Lucena, David, Russo, Virginie, Mena Barragán, Teresa, Ortiz Mellet, Carmen, et. al.:
The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Architectural Parameters With Cyclodextrin-Based Iminosugar Click Clusters. En: Chemistry: A European Journal. 2011. Vol. 17. Pag. 13825-13831. 10.1002/chem/201102266

Rodríguez Lucena, David, Gaboriau, François, Rivault, Freddy, Schalk, Isabelle J., Lescoat, Gerard, et. al.:
Synthesis and Biological Properties of Iron Chelators Based on a Bis-2-(2-Hydroxy-Phenyl)-Thiazole-4-Carboxamide or -Thiocarboxamide (Bhptc) Scaffold. En: Bioorganic & Medicinal Chemistry. 2010. Vol. 18. Pag. 689-695

Rodríguez Lucena, David, Ortiz Mellet, Carmen, Jaime Cardiel,Carlos, Burusko, Kepa, Garcia Fernandez, Jose Manuel, et. al.:
Size-Tunable Trehalose-Based Nanocavities: Synthesis, Structure, and Inclusion Properties of Large-Ring Cyclotrehalans. En: The Journal of Organic Chemistry. 2009. Vol. 74. Núm. 8. Pag. 2997-3008

Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Alvarez Gonzalez, Eleuterio, Jaime Cardiel,Carlos, Pérez Mirón,Javier, et. al.:
Synthesis, Structure, and Inclusion Capabilities of Trehalose-Based Cyclodextrin Analogues (Cyclotrehalans). En: The Journal of Organic Chemistry. 2008. Vol. 73. Núm. 8. Pag. 2967-2979

Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Alvarez Gonzalez, Eleuterio, Jaime Cardiel,Carlos, Pérez Mirón,Javier, et. al.:
Review/Reseña de Libro: Synthesis, Structure, and Inclusion Capabilities of Trehalose-Based Cyclodextrin Analogues (Cyclotrehalans). En: SYNFACTS Highlights in Current Synthetic Organic Chemistry. 2008. Vol. 7. Pag. 701-701. 10.1055/s-2008-1077802

Benito Hernandez, Juan Manuel, Rodríguez Lucena, David, Jimenez Blanco, Jose Luis, Ortiz Mellet, Carmen, García Fernández, José Manuel:
Trehalose-Based Cyclodextrin Analogs: Cyclotrehalans (Cts). En: Journal of Inclusion Phenomena and Molecular Recognition in Chemistry. 2007. Vol. 57. Núm. 1-4. Pag. 147-150

Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel:
Promoting Helicity in Carbohydrate-Containing Foldamers Through Long-Range Hydrogen Bonds. En: Chemical Communications. 2007. Núm. 8. Pag. 831-833

Gomez Garcia, Marta, Benito Hernandez, Juan Manuel, Rodríguez Lucena, David, Yu, Jian Xin, Chmusrki, Kazimierz, et. al.:
Probing Secondary Carbohydrate-Protein Interactions With Highly Dense Cyclodextrin-Centered Heteroglycoclusters: the Heterocluster Effect. En: Journal of Physics and Chemistry of Solids. 2005. Vol. 127. Núm. 22. Pag. 7970-7971

Garcia Moreno, María Isabel, Rodríguez Lucena, David, Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel:
Pseudoamide-Type Pyrrolidine and Pyrrolizidine Glycomimetics and Their Inhibitory Activities Against Glycosidases. En: The Journal of Organic Chemistry. 2004. Vol. 69. Núm. 10. Pag. 3578-3581

Aportaciones a Congresos

Rodríguez Lucena, David, García, Francisco Javier, Lopes da Costa, Tania Isabel, Pedrosa Poyato, Jose Maria:
Expanding the PIZOF Family for Fluorescence Array-Based Chemical Sensing. Poster en Congreso. 1st Mediterranean Conference on Porous Materials. Rethymno, Creta, Grecia. 2023

Benito Hernandez, Juan Manuel, Pflueger, Iris, Rodríguez Lucena, David, Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel:
Tailoring self-assembling and targeting capabilities of CD-based nanoparticles for gene delivery. Comunicación en congreso. XI Jornadas de Carbohidratos. Logroño (España). 2014

Rodríguez Lucena, David, Pflueger, Iris, Méndez Ardoy, Alejandro, Benito Hernandez, Juan Manuel, Ortiz Mellet, Carmen, et. al.:
Synthesis and Gene Transfer Capabilities of Cyclic Polyamine-Grafted Amphiphilic Cyclodextrins. Poster en Congreso. 26th International Carbohydrate Symposium. 2012

Rodríguez Lucena, David, Pflueger, Iris, Méndez Ardoy, Alejandro, Benito Hernandez, Juan Manuel, Ortiz Mellet, Carmen, et. al.:
Synthesis and Gene Transfer Capabilities of Cyclic Polyamine-Grafted Amphiphilic Cyclodextrins. Comunicación en congreso. 26th International Carbohydrate Symposium. Madrid (Espa?a). 2012

Rodríguez Lucena, David, Decroocq, Camille, Russo, Virginie, Iehl, Julien, Jimenez Blanco, Jose Luis, et. al.:
DNJ-[60]Fullerene and DNJ-bCD conjugates: Multivalent Effect on Glycosidase Inhibition. Comunicación en congreso. XXIV Reunión Bienal de Química Orgánica. Donostia, San Sebastian, Espa?a. 2012

Rodríguez Lucena, David, Decroocq, Camille, Russo, Virginie, Mena Barragán, Teresa, Nierengarten, Jean François, et. al.:
The Multivalent Effect in Glycosidase Inhibition. Poster en Congreso. First Biennial Meeting Chemical Biology Group. Santiago de Compostela, Spain. 2012

Jimenez Blanco, Jose Luis, Sylla, Balla, Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Ortiz Mellet, Carmen, et. al.:
Estudio Comparativo de las Propiedades Conformacionales y Supramoleculares de Alfa- y Beta-Glicosiltioureas. Poster en Congreso. XXXI Reunión Bienal de la Real Sociedad Española de Química. Toledo. 2007. Libro de Resumenes de la XXXI Reunion Bienal de la RSEQ. G1-P93. G1-P93

Benito Hernandez, Juan Manuel, Rodríguez Lucena, David, Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel:
Trehalose-Based Cyclodextrin Analogs: Cyclotrehalins. Poster en Congreso. XIII International Cyclodextrin Symposium. Torino, Italia. 2006. XIII International Cyclodextrin Symposium. 1p14. 1p14

Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Pérez Mirón,Javier, Jaime Cardiel,Carlos, Ortiz Mellet, Carmen, et. al.:
Glyconanocavities: Cyclotrehalans VS Cyclodextrins. Ponencia en Congreso. VIII Jornadas de Carbonhidratos. Alcal? de Henares, Madrid. 2006. VIII Jornadas de Carbohidratos. Co4. Co4

Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel:
Cyclotrehalines: Strategies Towards Tailor-Made Functional Mimics of Cyclodextrins. Poster en Congreso. European Carbohydrate Symposium. Bratislava (Eslovaquia). 2005. 13th European Carbohydrate Symposium. P49. P49

Garcia Fernandez, Jose Manuel, Ortiz Mellet, Carmen, Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Jimenez Blanco, Jose Luis:
Glyconanocavities: Cyclodextrins and More. Conferencia Congreso no publicada. New Aspects of Macro and Cyclic Molecular Chemistry. Atsugi, Jap?N. 2005. New Aspects of Macro and Cyclic Molecular Chemistry. --. --

Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel:
Trehalose-Based Cyclodextrin Analogs: Cyclotrehalins. Poster en Congreso. 3rd Iberian Carbohydrate Meeting . Coimbra Portugal. 2005. 6th International Meeting of the Portuguese Carbohydrate Group and 3rd Iberian Carbohydrate Meeting. 102. 102

Gomez Garcia, Marta, Benito Hernandez, Juan Manuel, Rodríguez Lucena, David, Yu, Jian Xin, Ortiz Mellet, Carmen, et. al.:
Hyperbranched Cyclodextrin As Glycocalix Surrogates: the Heterocluster Effect. Poster en Congreso. 3rd Iberian Carbohydrate Meeting . Coimbra Portugal. 2005. 6th International Meeting of the Portuguese Carbohydrate Group and 3rd Iberian Carbohydrate Meeting. 111. 111

Gomez Garcia, Marta, Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel, et. al.:
Cyclodextrin Polyconjugates: Inclusion, Lectin Binding and Drug Carrier Capabilities. Conferencia Congreso no publicada. International Carbohydrate Symposium. Glasgow. 2004. 22nd International Carbohydrate Symposium. Book of Abstracts. C17. C17

Gomez Garcia, Marta, Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel, et. al.:
Cyclodextrin Polyconjugates: Inclusion, Lectin Binding and Drug Carrier Capabilities. Poster en Congreso. International Carbohydrate Symposium. Glasgow. 2004. 22nd International Carbohydrate Symposium. Book of Abstracts. P86. P86

Gomez Garcia, Marta, Rodríguez Lucena, David, Benito Hernandez, Juan Manuel, Defaye, Jacques, Ortiz Mellet, Carmen, et. al.:
S?Ntesis de Glicoconjugados de Ciclodextrinas y Estudio de Sus Propiedades Como Transportadores Espec?Ficos de F?Rmacos. Poster en Congreso. VII Jornadas de Carbohidratos. Tarragona. 2004. VII Jornadas de Carbohidratos. C4. C4

Gomez Garcia, Marta, Rodríguez Lucena, David, Ortiz Mellet, Carmen, Defaye, Jacques, Garcia Fernandez, Jose Manuel:
Ciclodextrinas Hiperrramificadas: S?Ntesis y Evaluaci?N Biol?Gica. Comunicación en congreso. Centenario de las Reales Sociedades de F?SICA y Qu?Mica. XXIX Reuni?N Bienal de la Rse. 2003. XXIX Reuni?N Bienal de la Real Sociedad Espa?Ola de F?SICA - Centenario de las Reales Sociedades de F?SICA y Qu?Mica. XXIX Reuni?N Bienal de F?SICA ( a?o: 2003, Difusi?N: Nacional ). S1p118. S1p18

Gomez Garcia, Marta, Rodríguez Lucena, David, Ortiz Mellet, Carmen, Yu, Jian Xin, Defaye, Jacques, et. al.:
Hyperbranched Cyclodextrin Glycodendron Conjugates As Biomimetic Carriers. Poster en Congreso. 12th Europena Carbohydrate Symposium. 2003. 12th European Carbohydrate Symposium. Pb125. Pb125

Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel, Defaye, Jacques, Benito Hernandez, Juan Manuel, Gomez Garcia, Marta, et. al.:
Multivalent Cyclodextrins: Biomimetic Vehicles for Drug Delivery. Conferencia Congreso no publicada. 5th International Meeting of the Portuguese Carbohydrate Group. Covilha, Portugal. 2003. 5th International Meeting of the Portuguese Carbohydrate Group. Il04. Il04

Rodríguez Lucena, David, Rubio Castillo, Enrique Miguel, Ortiz Mellet, Carmen, Garcia Fernandez, Jose Manuel:
Synthesis of Fructose Mimics and Profiling Og Their Glycosidase Inhibitory Properties. Poster en Congreso. II Iberian Carbohydrate Meeting. Ronda (Espa?a). 2002. II Iberian Carbohydrates Meeting. P-A23. P-A23

Patentes:

Rodríguez Lucena, David, Mislin, Gäetan L. A., Lescoat, Gerard, Schalk, Isabelle J., Gaboriau, François:
Novel Compunds, Preparations and Uses Thereof. Patente de invención, Propiedad industrial. Solicitud: 2008-10-10