Antonio Javier Moreno Pérez
Telefono: 954553893
Email: Solicitar correo
Perfil en ORCID: 0000-0003-4908-8958
Perfil en WOS: E-9364-2017
Perfil en Scopus: 17434983400
Perfil en Dialnet: 2961365

Grupo de Investigación: Microorganismos Eucariotas
Departamento/Unidad: Microbiología
Situación profesional: Plan Propio-Acceso

Responsable de los siguientes proyectos/ayudas en la US:

• Contrato con empresas (Arts. 68/83 LOU):
  • Producción de cepas de hongos filamentosos con interés industrial (5310/2029)
  • Puesta a punto de producción de compuestos de interés industrial mediante fermentación microbiana (4940/2029)
  
  

Participa en los siguientes proyectos/ayudas en la US:

• Proyecto de investigación:
  • Evaluación de la leguminosa costera Retama monosperma (L.) Boiss. Como nueva fuente proteica en alimentación animal (RETFEED) (PROYEXCEL_00708 - Equipo Colaborador (altas/bajas))
  • Efecto de los factores abióticos en la producción de metabolitos secundarios con potencial fitoterapéutico en una especie costera (Glaucium flavum Crantz) (US-1380868 - Equipo Colaborador (altas/bajas))
  • Evaluación del Potencial del Hinojo Marino (Crithmum Maritimum L.) Como Cultivo Generador de Múltiples Productos de Interés Bajo Diferentes Condiciones Ambientales (RTI2018-099260-A-I00 - Contratado)
  
  

Cobertura de la base de datos de proyectos, véase aqui

Publicaciones:

Publicaciones en Revistas

Martins Noguerol, Raquel, Rico Jiménez, Diego, Matias Resina, Luis, Pérez Ramos, Ignacio Manuel, Moreira, Xoaquin, et. al.:
Effects of Drought and Increased Temperature on Phytochemical Traits of the Edible Halophyte Crithmum Maritimum: Perspectives for Future Climatic Scenarios. En: Environmental and Experimental Botany. 2024. Vol. 226. Núm. 105924. Pag. 1-11. https://doi.org/10.1016/j.envexpbot.2024.105924

De Andrés, Cristina, Moreno Pérez, Antonio Javier, Villoslada, Mónica, Halsey, Kirstie, Martínez Force, Enrique, et. al.:
Characterisation of fatty acyl reductases of sunflower (Helianthus annuus L.) seed. En: Plant Science. 2024. Vol. 341. 10.1016/j.plantsci.2024.111992

Makni, Salim, Acket, Sébastien, Guenin, Stéphanie, Afensiss, Sana, Guellier, Adeline, et. al.:
Arabidopsis seeds altered in the circadian clock protein TOC1 are characterized by higher level of linolenic acid. En: Plant Science. 2024. Vol. 344. 10.1016/j.plantsci.2024.112087

Garcés Mancheño, Rafael, De Andrés, Cristina, Venegas Calerón, Monica, Martínez Force, Enrique, Moreno Pérez, Antonio Javier, et. al.:
Characterization of sunflower seed and oil wax ester composition by GC/ MS, a final evaluation. En: LWT-Food Science and Technology. 2023. Vol. 173. https://doi.org/10.1016/j.lwt.2022.114365

Garcés Mancheño, Rafael, Martínez Force, Enrique, Venegas Calerón, Monica, Moreno Pérez, Antonio Javier, Salas Liñán, Joaquín Jesús:
A GC/MS method for the rapid determination of disaturated triacylglycerol positional isomers. En: Food Chemistry. 2023. Vol. 409. https://doi.org/10.1016/j.foodchem.2022.135291

Martins Noguerol, Raquel, Pérez Ramos , Ignacio M., Matias Resina, Luis, Moreira, Xoaquín, Francisco, Marta, et. al.:
Crithmum maritimum seeds, a potential source for high-quality oil and phenolic compounds in soils with no agronomical relevance. En: Journal of Food Composition and Analysis. 2022. Vol. 108. 10.1016/j.jfca.2022.104413

Martins Noguerol, Raquel, Matías , Luis, Pérez Ramos , Ignacio Manuel, Moreira, Xoaquín, Muñoz Vallés , Sara, et. al.:
Differences in nutrient composition of sea Fennel (Crithmum maritimum) grown in different habitats and optimally controlled growing conditions. 2022. Vol. 106. 10.1016/j.jfca.2021.104266

Martins Noguerol, Raquel, Acket, Sebastien, Troncoso Ponce, Manuel Adrián, Garcés Mancheño, Rafael, Venegas Calerón, Monica, et. al.:
Characterization and impact of sunflower plastidial octanoyltransferases (Helianthus annuus L.) on oil composition. En: Journal of Plant Physiology. 2022. Vol. 274. https://doi.org/10.1016/j.jplph.2022.153730

Sánchez Álvarez, Alfonso J., Ruiz López, Noemí, Moreno Pérez, Antonio Javier, Venegas Calerón, Monica, Martínez Force, Enrique, et. al.:
Metabolism and accumulation of hydroxylated fatty acids by castor (Ricinus comunis) seed microsomes. En: Plant Physiology and Biochemistry. 2022. Vol. 170. Pag. 266-274. https://doi.org/10.1016/j.plaphy.2021.12.010

González Thuillier, Irene, Venegas Calerón, Monica, Moreno Pérez, Antonio Javier, Salas Liñán, Joaquín Jesús, Garcés Mancheño, Rafael, et. al.:
Sunflower (Helianthus annuus) fatty acid synthase complex: ß-Ketoacyl-[acyl carrier protein] reductase genes. En: Plant Physiology and Biochemistry. 2021. Vol. 166. Pag. 689-699. https://doi.org/10.1016/j.plaphy.2021.06.048

Rodriguez Rodríguez, Manuel Fernando, Moreno Pérez, Antonio Javier, Makni, S., Troncoso Ponce, Manuel Adrián, Acket, Sébastien, et. al.:
Lipid profiling and oil properties of Camelina sativa seeds engineered to enhance the production of saturated and omega-7 fatty acids. En: Industrial Crops and Products. 2021. Vol. 170. https://doi.org/10.1016/j.indcrop.2021.113765

Martins Noguerol, Raquel, Acket, Sébastien, Troncoso Ponce, Manuel Adrián, Garcés Mancheño, Rafael, Thomasset, Brigitte, et. al.:
Characterization of Helianthus annuus Lipoic Acid Biosynthesis: The Mitochondrial Octanoyltransferase and Lipoyl Synthase Enzyme System. En: Frontiers in Plant Science. 2021. Vol. hal-03507054. 10.3389/fpls.2021.781917

Moreno Pérez, Antonio Javier, Santos Pereira, Jose M., Martins Noguerol, Raquel, De Andrés Gil, Cristina, Troncoso Ponce, Manuel Adrián, et. al.:
Genome-Wide Mapping of Histone H3 Lysine 4 Trimethylation (H3K4me3) and Its Involvement in Fatty Acid Biosynthesis in Sunflower Developing Seeds. En: Plants. 2021. Vol. 10. Núm. 4. https://doi.org/10.3390/plants10040706

Martins Noguerol, Raquel, De Andrés Gil, Cristina, Garcés Mancheño, Rafael, Salas Liñán, Joaquín Jesús, Martínez Force, Enrique, et. al.:
Characterization of the acyl-ACP thioesterases from Koelreuteria paniculata reveals a new type of FatB thioesterase. En: Heliyon. 2020. Vol. 6. Núm. e05237. 10.1016/j.heliyon.2020.e05237

Mapelli, Ana, Sánchez, Rosario, Pan, Xue, Moreno Pérez, Antonio Javier, Garcés Mancheño, Rafael, et. al.:
Functional characterization of lysophosphatidylcholine:acyl-Coa acyltransferase genes from sunflower (Helianthus annuus L.). En: Frontiers in Plant Science. 2020. Vol. 11. 10.3389/fpls.2020.00403

Martins Noguerol, Raquel, Moreno Pérez, Antonio Javier, Acket, Sebastien, Troncoso Ponce, Manuel Adrián, Garcés Mancheño, Rafael, et. al.:
Impact of sunflower (Helianthus annuus L.) plastidial lipoyl synthases genes expression in glycerolipids composition of transgenic Arabidopsis plantsArtículo. En: Scientific Reports. 2020. Vol. 10. 10.1038/s41598-020-60686-z

González Mellado, Damián, Salas Liñán, Joaquín Jesús, Venegas Calerón, Monica, Moreno Pérez, Antonio Javier, Garcés Mancheño, Rafael, et. al.:
Functional characterization and structural modelling of Helianthus annuus (sunflower) ketoacyl-CoA synthases and their role in seed oil composition. En: Planta. 2019. Vol. 249. Pag. 1823-1836. 10.1007/s00425-019-03126-1

Martins Noguerol, Raquel, Moreno Pérez, Antonio Javier, Acket, Sebastien, Makni, Salim, Garcés Mancheño, Rafael, et. al.:
Lipidomic Analysis of Plastidial Octanoyltransferase Mutants of Arabidopsis thaliana. En: Metabolites. 2019. Vol. 9. Núm. 10. 10.3390/metabo9100209

Sánchez Álvarez, Alfonso J., Ruiz López, Noemí, Moreno Pérez, Antonio Javier, Martínez Force, Enrique, Garcés Mancheño, Rafael, et. al.:
Agrobacterium-Mediated Transient Gene Expression in Developing Ricinus communis Seeds: A First Step in Making the Castor Oil Plant a Chemical Biofactory. En: Frontiers in Plant Science. 2019. Vol. 10. Núm. 1410. Pag. 1-11. doi: 10.3389/fpls.2019.01410

Aznar Moreno, José Antonio, Sánchez, Rosario, Martínez Force, Enrique, Moreno Pérez, Antonio Javier, Venegas Calerón, Monica, et. al.:
New insights into sunflower (Helianthus annuus L.) FatA and FatB thioesterases, their regulation, structure and distribution. En: Frontiers in Plant Science. 2018. 10.3389/fpls.2018.01496

Troncoso Ponce, Manuel Adrián, Sánchez, Rosario, Venegas Calerón, Monica, Moreno Pérez, Antonio Javier, Garcés Mancheño, Rafael, et. al.:
Molecular and biochemical characterization of the sunflower (Helianthus annuus L.) cytosolic and plastidial enolases in relation to seed development. En: Plant Science. 2018. Vol. 272. Pag. 117-130. https://doi.org/10.1016/j.plantsci.2018.04.007

Salas Liñán, Joaquín Jesús, Martínez Force, Enrique, Harwood, John L, Venegas Calerón, Monica, Aznar Moreno, José Antonio, et. al.:
Biochemistry of high stearic sunflower, a new source of saturated fats. En: Progress in Lipid Research. 2014. Vol. 55. Pag. 30-42. 10.1016/j.plipres.2014.05.001

Moreno Pérez, Antonio Javier, Venegas Calerón, Monica, Vaistij, Fabian e, Salas Liñán, Joaquín Jesús, Larson, Tony R, et. al.:
Effect of a mutagenized acyl-ACP thioesterase FATA allele from sunflower with improved activity in tobacco leaves and Arabidopsis seeds. En: Planta. 2014. Vol. 239. Núm. 3. Pag. 667-677. 10.1007/s00425-013-2003-0

Moreno Pérez, Antonio Javier, Venegas Calerón, Monica, Vaistij, Fabián, Salas Liñán, Joaquín Jesús, Larson, Tony, et. al.:
Reduced expression of FatA thioesterases in Arabidopsis affects the oil content and fatty acid composition of the seeds. En: Planta. 2012. Vol. 235. Pag. 629-639. 10.1007/s00425-011-1534-5

Moreno Pérez, Antonio Javier, Martínez Force, Enrique, Garcés Mancheño, Rafael, Salas Liñán, Joaquín Jesús:
Sphingolipid base modifying enzymes in sunflower (Helianthus annuus): expression profiles of a C4-hydroxylase gene and of a new paralogous ¿8-desaturase isoenzyme. En: Journal of Plant Physiology. 2011. Vol. 168. Núm. 8. Pag. 831-839. 10.1016/j.jplph.2010.11.015

Moreno Pérez, Antonio Javier, Sánchez García, Alicia, Salas Liñán, Joaquín Jesús, Garcés Mancheño, Rafael, Martínez Force, Enrique:
Acyl-Acp Thioesterases from Macadamia (Macadamia Tetraphylla) Nuts: Cloning, Characterization and Their Impact on Oil Composition. En: Plant Physiology and Biochemistry. 2011. Vol. 49. Pag. 82-87

Sánchez García, Alicia, Moreno Pérez, Antonio Javier, Muro Pastor, Alicia Maria, Salas, Joaquín J., Garcés Mancheño, Rafael, et. al.:
Acyl-Acp Thioesterases from Castor (Ricinus Communis L.):an Enzymatic System Appropriate for High Rates of Oil Synthesis and Accumulation. En: Phytochemistry: the International Journal of Plant Chemistry, Plant Biochemistry and Molecular Biology. 2010. Vol. 71. Pag. 860-869

Moreno Pérez, Antonio Javier, Martínez Force, Enrique, Garcés Mancheño, Rafael, Salas Liñán, Joaquín Jesús:
Phospholipase Dalpha from Sunflower (Helianthus Annuus): Cloning and Functional Characterization. En: Journal of Plant Physiology. 2010. Vol. 167. Pag. 503-511

Salas Liñán, Joaquín Jesús, Moreno Pérez, Antonio Javier, Martínez Force, Enrique, Garcés Mancheño, Rafael:
Characterization of the Glycerolipid Composition of a High-Palmitoleic Acid Sunflower Mutant. En: European Journal of Lipid Science And Technology. 2007. Vol. 109. Núm. 6. Pag. 591-599

Aportaciones a Congresos

Salas Liñán, Joaquín Jesús, Sánchez Álvarez, Alfonso J., Moreno Pérez, Antonio Javier, Martínez Force, Enrique, Garcés Mancheño, Rafael, et. al.:
Oilseed lipid biotechnology for better food and biomaterials. Ponencia en Congreso. Symposium on Small Molecules in Plant Research: Chemistry and Biology Come Together. Valencia, Spain. 2019

Moreno Pérez, Antonio Javier, Santos Pereira, José María, Troncoso Ponce, Manuel Adrián, Garcés Mancheño, Rafael, Salas Liñán, Joaquín Jesús, et. al.:
Genome-wide mapping of histone H3 lysine 4 trimethylation (H3K4me3) in Helianthus annuus developing seeds. Poster en Congreso. 17th Euro Fed Lipid Congress and Expo. ¿Oils, Fats and Lipids: Driving Science and Technology to new Horizons. Seville, Spain. 2019

Martins Noguerol, Raquel, De Andrés, Cristina, Garcés Mancheño, Rafael, Salas Liñán, Joaquín Jesús, Martínez Force, Enrique, et. al.:
Cloning and characterization of two acyl-ACP thioesterases from Koelreuteria paniculate. Poster en Congreso. 17th Euro Fed Lipid Congress and Expo. ¿Oils, Fats and Lipids: Driving Science and Technology to new Horizons. Seville, Spain. 2019

Martins Noguerol, Raquel, Moreno Pérez, Antonio Javier, Acket, S, Garcés Mancheño, Rafael, Salas Liñán, Joaquín Jesús, et. al.:
Effect of sunflower (Helianthus annuus L.) lipoic acid metabolism in plastidial fatty acids biosynthesis. Poster en Congreso. 17th Euro Fed Lipid Congress and Expo. ¿Oils, Fats and Lipids: Driving Science and Technology to new Horizons. Seville, Spain. 2019

Martins Noguerol, Raquel, Moreno Pérez, Antonio Javier, Acket, Sebastien, Garcés Mancheño, Rafael, Troncoso Ponce, Manuel Adrián, et. al.:
Sunflower (Helianthus annuus) plastidial lipoyl synthase genes and their impact on glycerolipid rearrangement in Arabidopsis. Ponencia en Congreso. 9th European Symposium on Plant Lipids. Marseille, France. 2019

Sánchez Álvarez, Alfonso J., Moreno Pérez, Antonio Javier, Garcés Mancheño, Rafael, Ruiz López, Noemí, Salas Liñán, Joaquín Jesús:
Genetic engineering of castor bean (Ricinus communis). Poster en Congreso. Plant Lipids: Structure, Metabolism and Function. Galveston, TX, USA. 2019

Sánchez Álvarez, Alfonso J., Salas Liñán, Joaquín Jesús, Ruiz López, Noemí, Garcés Mancheño, Rafael, Martínez Force, Enrique, et. al.:
Biotechnology Applied to Castor Bean Plant (Ricinus communis), a Potential Biofactory for Specialty Oils. Poster en Congreso. 17th Eurofeed lipid congress and expo. Instituto de la grasa, Sevilla. 2019

Salas Liñán, Joaquín Jesús, Sánchez Álvarez, Alfonso J., Ruiz López, Noemí, Martínez Force, Enrique, Moreno Pérez, Antonio Javier, et. al.:
Flash Talk: Studies on the Ability of Castor Seed to Accumulate Unusual Fatty Acids other than Ricinoleic. Comunicación en congreso. 17th Eurofeed lipid congress and expo. Instituto de la grasa, Sevilla. 2019

Moreno Pérez, Antonio Javier, Garcés Mancheño, Rafael, Martínez Force, Enrique, Salas Liñán, Joaquín Jesús:
Genetic engineering of castor bean (Ricinus comunis). Poster en Congreso. Plant Lipids: Structure, Metabolism and Function. Galveston, Tx, USA. 2019

Righini, D., Zanetti, F., Martínez Force, Enrique, Moreno Pérez, Antonio Javier, Di Girolamo, G., et. al.:
The Effect of Temperature on Fatty Acids Biosynthesis in Camelina Seeds. Poster en Congreso. 15th Euro Fed Lipid Congress: Oil, fats and Lipids: New technologies and Applications for a healhier life. Uppsala, Suecia. 2017

Moreno Pérez, Antonio Javier:
Papel de enzimas celulolíticas en la degradación de material lignocelulósico. Mesa redonda de Congreso. Primeras Jornadas Españolas de Biocatálisis. Madrid, España. 2015

Moreno Pérez, Antonio Javier:
Molecular mechanisms of cellulose hydrolysis. Mesa redonda de Congreso. 36th Symposium on Biotechnology for Fuels and Chemicals. Clearwater Beach, Florida. EE.UU. 2014

Moreno Pérez, Antonio Javier:
Evolution of Cellulolitic Enzymes. Mesa redonda de Congreso. 2nd Applied Synthetic Biology in Europe. Málaga, España. 2013

Moreno Pérez, Antonio Javier:
Cellulolytic enzymes in the second-generation bioethanol production. Mesa redonda de Congreso. 11th European Conference on Fungal Genetics. Marburg, Alemania. 2012

Moreno Pérez, Antonio Javier, Vaistij, F.E., Graham, Ian A., Salas Liñán, Joaquín Jesús, Garcés Mancheño, Rafael, et. al.:
Lipid Characterization of an Arabidopsis Mutant With Lower Expression of Acyl-Acp Thioesterase A. Poster en Congreso. XVII Congress of the Federation of European Societies of Plant Biology. Valencia, España. 2010. XVII Congress of the Federation of European Societies of Plant Biology (Fespb). 166. 166

Moreno Pérez, Antonio Javier, Salas Liñán, Joaquín Jesús, Garcés Mancheño, Rafael, Martínez Force, Enrique:
Modification of the Acil-Acp Thioesterase Type a from Sunflower (Helianthus Annuus L.) by Means of Site Directed Mutagenesis. Comunicación en congreso. 4th European Symposium on Plant Lipids. Gottingen (Alemania). 2009. 4th European Symposium on Plant Lipids. 57. 57

Sánchez García, Alicia, Moreno Pérez, Antonio Javier, Garcés Mancheño, Rafael, Martínez Force, Enrique:
Clonación y Caracterización de las Acil-Acp Tioesterasas de Ricinus Communis L. Poster en Congreso. IX Reunión de Biología Molecular de Plantas. Santiago de Compostela (España). 2008. IX Reunión de Biologia Molecular de Plantas. 66. 66

Moreno Pérez, Antonio Javier, Martínez Force, Enrique, Garcés Mancheño, Rafael, Salas Liñán, Joaquín Jesús:
Biochemical and Molecular Characterization of a Phospholipase Dalpha from Sunflower (Helianthus Annuus). Comunicación en congreso. 18th International Symposium in Plant Lipids. Burdeos (Francia). 2008. 18th International Symposium in Plant Lipids. 167. 167

Moreno Pérez, Antonio Javier, Sánchez García, Alicia, Garcés Mancheño, Rafael, Martínez Force, Enrique:
Cloning and Characterization of Two Acyl-Acp Thioesterases from Castor Bean (Ricinus Communis L.). Comunicación en congreso. 18th International Symposium in Plant Lipids. Burdeos (Francia). 2008. 18th International Symposium in Plant Lipids. 143. 143

Martínez Force, Enrique, Salas Liñán, Joaquín Jesús, Venegas Calerón, Monica, Troncoso Ponce, Manuel Adrián, González Mellado, Damián, et. al.:
Designing Sunflower Oils for Healthy Foods. Comunicación en congreso. 6th Euro Fed Lipid Congress. Atenas, Grecia. 2008. 6th Euro Fed Lipid Congress: Oil, Fats and Lipids in the 3rd Millenium. 31. 31

Moreno Pérez, Antonio Javier, Salas Liñán, Joaquín Jesús, Garcés Mancheño, Rafael, Martínez Force, Enrique:
Modificación de las Acil-Acp Tioesterasas de Girasol Mediante Mutagénesis Dirigida. Comunicación en congreso. XVII Reunión Nacional de la Sociedad Española Fisiología Vegetal and X Congreso Hispano-Luso de Fisiología Vegetal. Alcalá de Henares, Madrid. 2007. XVII Reunión Nacional de la Sociedad Española Fisiología Vegetal and X Congreso Hispano-Luso de Fisiología Vegetal. 376. 376

Patentes:

Diez García, Bruno, Valbuena Crespo, Noelia, Reyes Sosa, Francisco Manuel, Moreno Pérez, Antonio Javier, Pérez Gómez, Dolores, et. al.:
Expression of Recombinant Beta-Xylosidase Enzymes. Patente de invención, Propiedad industrial. Solicitud: 2015-07-29

Reyes Sosa, Francisco Manuel, Diez García, Bruno, Valbuena Crespo, Noelia, Moreno Pérez, Antonio Javier, Pérez Gómez, Dolores, et. al.:
Cellulolytic Compositions Comprising Polysaccharide Monooxigenase Enzymes With Improved Activity. Patente de invención, Propiedad industrial. Solicitud: 2015-06-23

Diez García, Bruno, Valbuena Crespo, Noelia, Reyes Sosa, Francisco Manuel, Moreno Pérez, Antonio Javier, Pérez Gómez, Dolores, et. al.:
Improved Variants of Cellobiohydrolase I. Patente de invención, Propiedad industrial. Solicitud: 2015-04-08

Diez García, Bruno, Valbuena Crespo, Noelia, Reyes Sosa, Francisco Manuel, Moreno Pérez, Antonio Javier, Pérez Gómez, Dolores, et. al.:
Production of an Enzymatic Mixture Lacking Endoglucanase VI Activity. Patente de invención, Propiedad industrial. Solicitud: 2014-11-28

Diez García, Bruno, Gómez Rodríguez, Ana, Gil Martínez, Jorge, Valbuena Crespo, Noelia, Reyes Sosa, Francisco Manuel, et. al.:
Polypeptides With Polysaccharide Monooxygenase Activity and Use Thereof for the Production of Fermentable Sugars. Patente de invención, Propiedad industrial. Solicitud: 2014-02-07

Diez García, Bruno, Valbuena Crespo, Noelia, Gómez Rodríguez, Ana, Gil Martínez, Jorge, Moreno Pérez, Antonio Javier, et. al.:
Myceliophthora Thermophila Host Cell Expressing a Heterologous Alpha-Xilosidase Enzyme and Use Thereof in a Method for the Degradation Biomass. Patente de invención, Propiedad industrial. Solicitud: 2013-07-22

Diez García, Bruno, Gómez Rodríguez, Ana, Gil Martínez, Jorge, Valbuena Crespo, Noelia, Moreno Pérez, Antonio Javier, et. al.:
Expression of Recombinant Beta-Xylosidase Enzymes. Patente de invención, Propiedad industrial. Solicitud: 2013-05-20

Diez García, Bruno, Gómez Rodríguez, Ana, Gil Martínez, Jorge, Valbuena Crespo, Noelia, Moreno Pérez, Antonio Javier, et. al.:
Beta-Glucosidase Variants Having Reduced Transglycosylation Activity. Patente de invención, Propiedad industrial. Solicitud: 2013-05-10

Tesis dirigidas y co-dirigidas:

(Doctorando no grabado)
Síntesis de ácido lipoico en semillas de girasol y su posible papel en la regulación de la síntesis de ácidos grasos. Tesis Doctoral. 2020