Logotipo de Universidad de Sevilla
VICERRECTORADO DE INVESTIGACIÓN
Logotipo Andalucía Tech
Letras Universidad de Sevilla

Ficha personal - José Manuel García Heredia


José Manuel García Heredia
Telefono: 95.4489500 ext. 9101
Email: Solicitar correo
Perfil en ORCID: 0000-0003-3095-0050
Perfil en ResearcherID: M-5536-2016
Perfil en Scopus: 14018078100
Perfil en Dialnet: 3616788

Grupo de Investigación: CTS-025 Biologia Molecular del Cancer
Departamento/Unidad: Bioquímica Vegetal y Biología Molecular
Situación profesional: Profesor Titular de Universidad

Participa en los siguientes proyectos/ayudas en la US:

  • Proyecto de investigación:
    • Desvelando Nuevas Redes de Proteínas que Interaccionan con el Citocromo C: Análisis Comparativo Estructural y Funcional (BFU2012-31670 - Investigador)
    • Bases estructurales, reconocimiento molecular y análisis evolutivo del citocromo C, una proteína bifuncional modificada post- tradiccionalmente (BFU2009-07190 - Otro Investigador)
    • Búsqueda Estructural de Metaloproteínas Vegetales Capaces de Inhibir la Invasión Celular y Posterior Desarrollo del Parásito de la Malaria (P08-CVI-03876 - Contratado)
    • Análisis evolutivo y relación estructura-función del citocromo c y su equivalente metabólico, el citocromo c6, como inductores de muerte celular programada (BFU2006-01361 - Investigador)

  • Contrato con empresas (Arts. 68/83 LOU):
    • Análisis calorimétrico de la relación estructura-función de metaloproteínas (OG-088/04 - Becario)

  • Ayuda a la investigación:
    • Incentivo al Grupo de Investigación BIO-198 (2011/BIO-198 - Investigador)
    • Ayuda a la Consolidación del Grupo de Investigación BIO-198 (2008/BIO-198 - Investigador)
    • Ayuda a la Consolidación del Grupo de Investigación BIO-198 (2007/BIO-198 - Investigador)

Cobertura de la base de datos de proyectos, véase aqui


Publicaciones:

Publicaciones en Revistas
Macías García, Laura, M. Martínez Ballesteros, Luna, José María, Garcia Heredia, Jose Manuel, García Gutiérrez, Jorge, et. al.:
Autoencoded DNA Methylation Data to Predict Breast Cancer Recurrence: Machine Learning Models and Gene-Weight Significance. En: Artificial Intelligence in Medicine. 2020. https://doi.org/10.1016/j.artmed.2020.101976

Muñoz Galvan, Sandra, Rivero, Maria, Javier Peinado Serrano, Javier, Martinez , Julia, Fernández Fernández, M C, et. al.:
PAI1 Is a Marker of Bad Prognosis in Rectal Cancer but Predicts a Better Response to Treatment With PIM Inhibitor AZD1208. En: Cells. 2020. Vol. 9. :10.3390/cells9051071

Muñoz Galvan, Sandra, Felipe Abrio, Blanca, Garcia Carrasco, Miguel, Dominguez Piñol, Julia, Suárez Martínez, Elisa, et. al.:
New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools. En: Journal of Experimental & Clinical Cancer Research. 2019. Vol. 38. Núm. 234. Pag. 1-14. 10.1186/s13046-019-1245-5

Garcia Heredia, Jose Manuel, Carnero, a:
Review/Reseña: Dr. Jekyll and Mr. Hyde: MAP17's up-regulation, a crosspoint in cancer and inflammatory diseases. En: Molecular Cancer. 2018. Vol. 17. 10.1186/s12943-018-0828-7

Ferrer Sánchez, Irene, Quintanal Villalonga, Álvaro, Molina Pinelo, Sonia, Garcia Heredia, Jose Manuel, Perez, Marco, et. al.:
MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma. En: Journal of Experimental & Clinical Cancer Research. 2018. Vol. 37. 10.1186/s13046-018-0871-7

Garcia Heredia, Jose Manuel, Carnero, a:
NUMB and NUMBL differences in gene regulation. En: Oncotarget. 2018. Vol. 9. Núm. 10. Pag. 9219-9234. 10.18632/oncotarget.24186

Verdugo Sivianes, Eva María, Navas, Lola E., Molina Pinelo, Sonia, Ferrer Sánchez, Irene, Quintanal Villalonga, Álvaro, et. al.:
Coordinated downregulation of Spinophilin and the catalytic subunits of PP1, PPP1CA/B/C, contributes to a worse prognosis in lung cancer. En: Oncotarget. 2017. Vol. 8. Núm. 62. Pag. 105196-105210. doi: 10.18632/oncotarget.22111

Garcia Heredia, Jose Manuel, Lucena Cacace, Antonio, Verdugo Sivianes, Eva María, Perez, Marco, Carnero Moya, Amancio:
The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB. En: Clinical Cancer Research. 2017. 10.1158/1078-0432.ccr-16-2358

M. Martínez Ballesteros, Garcia Heredia, Jose Manuel, Nepomuceno Chamorro, Isabel de los Angeles, Riquelme Santos, José Cristóbal:
Machine learning techniques to discover genes with potential prognosis role in Alzheimer¿s disease using different biological sources. En: Information Fusion. 2017. Vol. 36. Pag. 114-129. 10.1016/j.inffus.2016.11.005

Perez, Marco, Peinado Serrano, Javier, Garcia Heredia, Jose Manuel, Felipe Abrio, Irene, Tous Rivera, Cristina, et. al.:
Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1). En: Oncotarget. 2016. Vol. 7. Núm. 41. Pag. 67033-67046. doi: 10.18632/oncotarget.11475

Garcia Heredia, Jose Manuel, Verdugo Sivianes, Eva María, Lucena Cacace, Antonio, Molina Pinelo, Sonia, Carnero, a:
Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy. En: Oncotarget. 2016. Vol. 7. Núm. 39. Pag. 63611-63628. 10.18632/oncotarget.11553

Garcia Heredia, Jose Manuel, Verdugo Sivianes, Eva M, Lucena Cacace, Antonio, Molina Pinelo, Sonia, Carnero Moya, Amancio:
Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy. En: Oncotarget. 2016. Vol. 7. Núm. 39. Pag. 63611-63628. 10.18632/oncotarget.11553

Sánchez Medina, Alejandro, Gil Pichardo, Alberto, Garcia Heredia, Jose Manuel, M. Martínez Ballesteros:
Discovery of Genes implied in Cancer by Genetic Algorithms and Association Rules. En: Lecture Notes in Computer Science. 2016. Vol. 9846. Pag. 694-705. 10.1007/978-3-319-32034-2_58

Garcia Heredia, Jose Manuel, Felipe Abrio, Blanca, Cano Gonzalez, David Antonio, Carnero Moya, Amancio:
Review/Reseña: Genetic modification of hypoxia signaling in animal models and its effect on cancer. En: Clinical & Translational Oncology. 2015. Vol. 17. Núm. 2. Pag. 90-102. 10.1007/s12094-014-1236-0

Díaz Moreno, Irene, Garcia Heredia, Jose Manuel, Gonzalez Arzola, Katiuska, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel:
Review/Reseña: Recent Methodological Advances in the Analysis of Protein Tyrosine Nitration. En: Chemphyschem. 2013. 10.1002/cphc.201300210

Díaz Moreno, Irene, Nieto Mesa, Pedro Manuel, Del Conte, Rebeca, Gairi, Margarida, Garcia Heredia, Jose Manuel, et. al.:
A non-damaging method to analyze the configuration and dynamics of nitrotyrosines in proteins. En: European Journal Of Organic Chemistry. 2012. Vol. 18. Núm. 13. Pag. 3872-3878. 10.1002/chem.201103413

Garcia Heredia, Jose Manuel:
Perturbation of the Redox Site Structure of Cytochrome c Variants upon Tyrosine Nitration. En: The Journal of Physical Chemistry B. 2012. Vol. 116. Núm. 19. Pag. 5694-5702. 10.1021/jp302301m

Garcia Heredia, Jose Manuel, Díaz Moreno, Irene, Díaz Quintana, Antonio, Orzáez, Mar, Navarro Carruesco, José Antonio, et. al.:
Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome. En: FEBS Letters. 2012. Vol. 586. Núm. 2. Pag. 154-158. 10.1016/j.febslet.2011.12.007

García Heredia, José Manuel, Salzano, Maria, Orzaez, Mar, Perez Paya, Enrique, Teixeira, Miguel, et. al.:
Tyrosine phosphorylation turns alkaline transition into a biologically relevant process and makes human cytochrome c behave as an anti-apoptotic switch. En: Journal of Biological Inorganic Chemistry. 2011. Vol. 16. Pag. 1155-1168. 10.1007/s00775-011-0804-9

Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, Salzano, Maria, Orzáez, Mar, Pérez Payá, Enrique, et. al.:
Tyrosine phosphorylation turns alkaline transition into a biologically relevant process and makes human cytochrome c behave as an anti-apoptotic switch. En: Journal of Biological Inorganic Chemistry. 2011. Vol. 16. Pag. 1155-1168. doi: 10.1007/s00775-011-0804-9

Díaz Moreno, Irene, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel:
Review/Reseña: Cytochrome c signalosome in mitochondria. En: European Biophysics Journal. 2011. Vol. 40. Pag. 1301-1315. 10.1007/s00249-011-0774-4

Díaz Moreno, Irene, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, Teixeira, Miguel, De la Rosa Acosta, Miguel Angel:
Nitration of tyrosines 46 and 48 induces the specific degradation of cytochrome c upon chage of the heme iron state to high spin. En: Biochimica et Biophysica Acta (BBA): Bioenergetics. 2011. Vol. 1807. Núm. 12. Pag. 1616-1623. 10.1016/j.bbabio.2011.09.012

Garcia Heredia, Jose Manuel, Díaz Moreno, Irene, Nieto Mesa, Pedro Manuel, Orzáez, Mar, Kocanis, Stella, et. al.:
Nitration of Tyrosine 74 Prevents Human Cytochrome C to Play a Key Role in Apoptosis Signaling by Blocking Caspase-9 Activation. En: Biochimica et Biophysica Acta (BBA): Bioenergetics. 2010. Pag. 981-993

Rodríguez Roldán, Vicente, Garcia Heredia, Jose Manuel, Navarro Carruesco, José Antonio, De la Rosa Acosta, Miguel Angel, Hervás Morón, Manuel:
Effect of Nitration on the Physicochemical and Kinetic Features of Wild-Type and Monotyrosine Mutants of Human Respiratory Cytochrome C. En: Biochemistry (Moscow). 2008. Vol. 47. Núm. 47. Pag. 12371-12379

Garcia Heredia, Jose Manuel, Hervás Morón, Manuel, De la Rosa Acosta, Miguel Angel, Navarro Carruesco, José Antonio:
Acetylsalicylic Acid Induces Programmed Cell Death in Arabidopsis Cell Cultures. En: Planta. 2008. Vol. 228. Núm. 1. Pag. 89-97

Rodríguez Roldán, Vicente, Garcia Heredia, Jose Manuel, Navarro Carruesco, José Antonio, Hervás Morón, Manuel, De la Cerda Haynes, Berta, et. al.:
A Comparative Kinetic Analysis of the Reactivity of Plant, Horse, and Human Respiratory Cytochrome C Towards Cytochrome C Oxidase. En: Biochemical and Biophysical Research Communications. 2006. Vol. 346. Núm. 3. Pag. 1108-1113

Aportaciones a Congresos
Verdugo Sivianes, Eva María, Navas, Lola E., Molina Pinelo, Sonia, Ferrer Sánchez, Irene, Quintanal Villalonga, Álvaro, et. al.:
Coordinated downregulation of spinophilin and the catalytic subunits of PP1, PPP1CA/B/C, contributes to worse prognosis in squamous cell carcinoma of the lung. Poster en Congreso. III National Congress for Young Researchers in Biomedicine. , , - Valencia, España. 2019

Verdugo Sivianes, Eva María, Felipe Abrio, Blanca, Otero, Daniel, Jiménez, Manuel Pedro, Navas, Lola E., et. al.:
Prognostic relevance of PP1 in breast cancer. Poster en Congreso. 25th Biennial Congress of the European Association for Cancer Research. - Amsterdam. 2018

Otero, Daniel, Muñoz Galvan, Sandra, Suárez Martínez, Elisa, Verdugo Sivianes, Eva María, Jiménez, Manuel Pedro, et. al.:
Hypoxia-induced PLD2 promotes tumorigenesis and stem cell-like properties in tumor cells. Poster en Congreso. 25th Biennial Congress of the European Association for Cancer Research. - Amsterdam. 2018

Perez, Marco, Muñoz Galvan, Sandra, Jiménez, Manuel Pedro, Marin Lopez, Juan José, Padillo, Jose Carlos, et. al.:
Orthotopic xenografts of colorectal hepatic metastases maintain morphological phenotypic and genetic characteristic of the original tumors. Comunicación en congreso. XV ASEICA International Congress. Sevilla, España. 2015

Perez, Marco, Muñoz Galvan, Sandra, Jiménez, Manuel Pedro, Marin Lopez, Juan José, Verdugo Sivianes, Eva María, et. al.:
Efficacy of CDK4 inhibition against sarcomas depends on their levels of CDK4 mRNA. Poster en Congreso. XV ASEICA International Congress. Sevilla, España. 2015

Díaz Moreno, Irene, Martínez Fábregas, Jónathan, Gonzalez Arzola, Katiuska, Cruz Gallardo, Isabel, Moreno Beltrán, José Blas, et. al.:
Biointeractomic scaffold hovering on cytochrome c under programmed cell death. Sesión plenaria en Congreso. XII PABMB CONGRESS XXXVI ANNUAL MEETING SOCIEDAD DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR DE CHILE XLIX ANNUAL MEETING SOCIEDAD ARGENTINA DE INVESTIGACIÓN BIOQUÍMICA Y BIOLOGÍA MOLECULAR LVI ANNUAL MEETING SOCIEDAD DE BIOLOGÍA DE CHILE 4th LATIN AMERICAN PROTEIN SOCIETY MEETING. Puerto Varas, Chile. 2013

Garcia Heredia, Jose Manuel, Guerra Castellano, Alejandra, Moreno Beltrán, José Blas, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel, et. al.:
Regulación de las funciones del citocromo c mediante fosforilación. Sesión no plenaria en Congreso. XXXVI Congreso de la Sociedad Española de Bioquímica y Biología Molecular (SEBBM). 2013

Díaz Moreno, Irene, Moreno Beltrán, José Blas, Guerra Castellano, Alejandra, Gonzalez Arzola, Katiuska, Garcia Heredia, Jose Manuel, et. al.:
How redox proteins form transient complexes in photosynthesis and respiration. Ponencia en Congreso. 9th EBSA European Biophysics Congress. Lisboa, Portugal. 2013

Moreno Beltrán, José Blas, Guerra Castellano, Alejandra, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel, et. al.:
NMR as a tool to analyze the structural basis for the different functional properties of phosphorylated cytochrome c. Comunicación en congreso. BioNMR Annual User Group 2013. Budapest, Hungría. 2013

Moreno Beltrán, José Blas, Gonzalez Arzola, Katiuska, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel:
Cytochrome c1, An Old Protein with Novel Functions. Comunicación en congreso. Young Scientists Program (YSP) / 12th YSF. 2012

Guerra Castellano, Alejandra, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, López Prados, Javier, Nieto Mesa, Pedro Manuel, et. al.:
Construction of a Mimetic Mutant of Cytochrome c Phosphorylated. Poster en Congreso. 12th Young Scientist Program. Costa Ballena, Cádiz, ESPAÑA. 2012

Montiel Leyva, Mercedes, Morell Jiménez, Valentina, Garcia Heredia, Jose Manuel, Salas Millan, Manuel Julian, Díaz Quintana, Antonio, et. al.:
22nd IUBMB Congress/37th FEBS Congress. Comunicación en congreso. 2nd Iubmb Congress/37th Febs Congress. Palacio de Congresos Sevilla. 2012

Garcia Heredia, Jose Manuel, Díaz Moreno, Irene, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel:
High spin nitrated cytochrome c is specifically degraded inside the cells. Poster en Congreso. 22nd IUBMB & 37th FEBS Congress. Palacio de Congresos Sevilla. 2012

Guerra Castellano, Alejandra, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, López Prados, Javier, Nieto, Pedro M., et. al.:
Construction of a mimetic mutant of cytochrome c phosphorylated at tyrosine 48 to further study its biological role in the transition from cell life to death. Poster en Congreso. 22nd IUBMB & 37th FEBS Congress. Palacio de Congresos Sevilla. 2012

Moreno Beltrán, José Blas, Gonzalez Arzola, Katiuska, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel, et. al.:
Cytochrome c1: an old protein with novel functions. Poster en Congreso. 22nd IUBMB & 37th FEBS Congress. Sevilla. 2012

Díaz Moreno, Irene, Garcia Heredia, Jose Manuel, Garcia Heredia, Jose Manuel, Salzano, Maria, Orzáez, Mar, et. al.:
Tyrosine Phosphorylation turns Alkaline Transition into a Biologically Relevant Process and makes Human Cytochrome c behave as an Anti-apoptotic Switch. Poster en Congreso. XI Congreso de la Sociedad de Biofísica de España. 2011

Aroca Aguilar, Angeles, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel, Díaz Moreno, Irene:
Post-transcriptional and post-translational regulation of programmed cell death. Ponencia en Congreso. Bio-NMR Users Meeting 2011. Brno, Czech Republic. 2011

Díaz Moreno, Irene, Garcia Heredia, Jose Manuel, Nieto Mesa, Pedro Manuel, Orzaez, Mar, Kocanis, Stella, et. al.:
Structural and Functional changes induced by tyrosine nitration in cytochrome c, a bi-functional protein. Poster en Congreso. OzBio2010: 12th IUBMB and the 21st FAOBMB & ComBio2010. 2010

De la Rosa Acosta, Miguel Angel, Garcia Heredia, Jose Manuel, Martínez Fábregas, Jónathan, Nieto Mesa, Pedro Manuel, Rubio Novella, Silvia, et. al.:
Structural and Functional Changes Induced by Tyrosine Nitration in Cytochrome C, a Bi-Functional Protein. Conferencia Congreso no publicada. 16th European Bioenergetics Conference. Varsovia. 2010. Actas del 16th European Bioenergetics Conference. 70. 73

Scheiba, Rafael, Aroca Aguilar, Mª Ángeles, Garcia Heredia, Jose Manuel, De la Rosa Acosta, Miguel Angel, Díaz Moreno, Irene:
Hur a RNA Binding Protein With Modular Assembly Exploring TS Secondary Structure, Thermal Stability and Phosphorylation. Poster en Congreso. XXXIII Congreso de la Sociedad Española de Bioquímica y Biología Molecular. Córdoba, España. 2010

Garcia Heredia, Jose Manuel, Salzano, Maria, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel, Díaz Moreno, Irene:
Modulation of Functional Properties of Cytochrome C by Phosphorylation. Comunicación en congreso. IV Spanish Portuguese Biophysical Congress. Zaragoza (Spain). 2010. IV Spanish Portuguese Biophysical Congress. 127. 127

Díaz Moreno, Irene, Garcia Heredia, Jose Manuel, Nieto Mesa, Pedro Manuel, Orzáez, Mar, Kocanis, Stella, et. al.:
Structural and Functional Changes Induced by Tyrosine Nitration in Cytochrome C: a Bi-Functional Protein. Poster en Congreso. 35th Febs Congress Molecules of Life. Göteborg, Suecia. 2010. Actas del 35th Febs Congress Molecules of Life. 17. 17

Scheiba, Rafael, Aroca Aguilar, Mª Ángeles, Garcia Heredia, Jose Manuel, De la Rosa Acosta, Miguel Angel, Díaz Moreno, Irene:
Biophysical Analysis of the RNA Binding Protein Hur With Regard to Its Modular Assembly and Post-Translational Modifications. Poster en Congreso. Workshop on Understanding Transient Molecular Interactions in Biology. Santander (ESPAÑA). 2010. Actas del Febs Workshop on Understanding Transient Molecular Interactions in Biology. 129. 129

Aroca Aguilar, Mª Ángeles, Scheiba, Rafael, Garcia Heredia, Jose Manuel, De la Rosa Acosta, Miguel Angel, Díaz Moreno, Irene:
Biophysical Characterization of the T-Cell-Restristed Intracellular Antigen-1 (Tia-1) Protein. Poster en Congreso. Workshop on Understanding Transient Molecular Interactions in Biology. Santander (ESPAÑA). 2010. Actas del Febs Workshop on Understanding Transient Molecular Interactions in Biology. 56. 56

Garcia Heredia, Jose Manuel, Díaz Moreno, Irene, Navarro Carruesco, José Antonio, Hervás Morón, Manuel, Nieto Mesa, Pedro Manuel, et. al.:
Cell Life (Respiration) Versus Cell Death (Apoptosis): Two Functions That Differ in the Lifetime of the Complexes Involving Cytochrome C. Poster en Congreso. Workshop on Understanding Transient Molecular Interactions in Biology. Santander (ESPAÑA). 2010. Actas del Febs Workshop on Understanding Transient Molecular Interactions in Biology. 82. 83

Salzano, Maria, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, De la Rosa Acosta, Miguel Angel, Díaz Moreno, Irene:
Phosphorylation of Cytochrome C: Thermal Stability, Alkaline Transition and Ability to Activate Caspase-9 of the Y48e and Y97e Mutants. Poster en Congreso. Workshop on Understanding Transient Molecular Interactions in Biology. Santander (ESPAÑA). 2010. Actas del Febs Workshop on Understanding Transient Molecular Interactions in Biology. 121. 122

Garcia Heredia, Jose Manuel, Díaz Moreno, Irene, Díaz Quintana, Antonio, Nieto Mesa, Pedro Manuel, Orzáez, Mar, et. al.:
Structural and Functional Bases of Post-Translationally Modified Cytochrome C, a Bifunctional Protein. Poster en Congreso. 21th Iubmb International Congress of Biochemistry and Molecular Biology and 12th Faobmb Congress. Shanghai, China. 2009. 21th Iubmb International Congress of Biochemistry and Molecular Biology and 12th Faobmb Congress. 68. 68

Díaz Moreno, Irene, Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, Nieto Mesa, Pedro Manuel, Orzáez, Mar, et. al.:
Structural and Functional Features of Post-Translationally Modified Cytochrome C, a Bifunctional Protein. Poster en Congreso. 34rd Febs Congress . Praga, República Checa. 2009. 34rd Febs Congress. 134. 134

Garcia Heredia, Jose Manuel, Hervás Morón, Manuel, De la Rosa Acosta, Miguel Angel, Navarro Carruesco, José Antonio:
Effect of Nitration of Respiratory Cytochrome C on Its Role As a Physiological Apoptosis-Inducing Agent. Comunicación en congreso. Febs Workshops on "Transient Interactions Between Biological Macromolecules. Santander (ESPAÑA). 2007. Abstracts of the Febs Worshop on Trends in Transient Interactions Between Biological Macromolecules. P14. P14

Garcia Heredia, Jose Manuel, Hervás Morón, Manuel, De la Rosa Acosta, Miguel Angel, Navarro Carruesco, José Antonio:
Efecto de la Modificación Química del Citocromo C Sobre su Capacidad para Inducir la Apoptosis. Poster en Congreso. XXX Congreso de la Sociedad Española de Bioquímica y Biología Molecular. , Málaga, España. 2007. XXX Congreso de la Sociedad Española de Bioquímica y Biología Molecular. 135. 135

Garcia Heredia, Jose Manuel, Hervás Morón, Manuel, De la Rosa Acosta, Miguel Angel, Navarro Carruesco, José Antonio:
Muerte Celular Programada en Arabidopsis Thaliana Inducida Por Ácido Acetilsalicílico. Poster en Congreso. XXIX Congreso de la SEBBM. Elche. 2006. XXIX Congreso de la SEBBM. 157. 157

Rodríguez Roldán, Vicente, Garcia Heredia, Jose Manuel, De la Cerda Haynes, Berta, Navarro Carruesco, José Antonio, Hervás Morón, Manuel, et. al.:
Caracterización Físico-Química del Citocromo C Respiratorio de Homo Sapiens Sapiens y Arabidopsis Thaliana en Estado Nativo y Nitrado. Comunicación en congreso. Congreso de la Sociedad Española de Bioquímica y Biología Molecular. Lleida, España. 2004. Libro de Actas de la SEBBM 2004. 229. 229

Garcia Heredia, Jose Manuel, Díaz Quintana, Antonio, López Prados, Javier, Nieto Mesa, Pedro Manuel, De la Rosa Acosta, Miguel Angel, et. al.:
Construction of a Mimetic Mutant of Cytochrome c Phosphorylated. Poster en Congreso

Guerra Castellano, Alejandra, Garcia Heredia, Jose Manuel, Moreno Beltrán, José Blas, López Prados, Javier, Nieto Mesa, Pedro Manuel, et. al.:
Structural Changes of Cytochrome c upon Phosphorylation Explain Differences in Functional Properties. Poster en Curso

Patentes:


De la Cerda Haynes, Berta, De la Rosa Acosta, Miguel Angel, Garcia Heredia, Jose Manuel, Hervás Morón, Manuel, Navarro Carruesco, José Antonio, et. al.:
Construcción Genética que Codifica para el Citocromo C y Procedimiento de Obtención. Patente de invención, Propiedad industrial. Solicitud: 2004-11-05

Vicerrectorado de Investigación. Universidad de Sevilla. Pabellón de Brasil. Paseo de las Delicias s/n. Sevilla