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Ficha personal - Ruth Hornedo Ortega


Ruth Hornedo Ortega
Telefono: 954556761
Email: Solicitar correo
Perfil en ORCID: 0000-0003-1898-8806
Perfil en ResearcherID: F-6822-2016

Grupo de Investigación: Derivados de la Uva
Departamento/Unidad: Nutrición y Bromatología, Toxicología y Medicina Legal
Situación profesional: Personal Investigador en Formación (Junta de Andalucia)

Responsable de los siguientes proyectos/ayudas en la US:

  • Ayuda a la investigación:
    • Caracterización química de bebidas obtenidas por fermentación. Determinación de la bioactividad de compuestos indólicos y polifenólicos frente a la agregación de péptidos relacionados con diferentes enfermedades degenerativas (PP2013-809)

Participa en los siguientes proyectos/ayudas en la US:

  • Proyecto de investigación:
    • Potencial Bioactivo de Metabolitos Sintetizados por Microorganismos Seleccionados y su Impacto en la Calidad y Seguridad de Bebidas Fermentadas (PID2019-108722RB-C32 - Equipo Trabajo (Solicitud))
    • Análisis Metabolómico y Evaluación de la Bioactividad de Compuestos Producidos por Levaduras Presentes en Alimentos (AGL2016-77505-C3-2-R - Equipo Trabajo (Solicitud))
    • Caracterización Química y Bioactividad de Compuestos Derivados de Aminoácidos Aromáticos Relacionados con el Metabolismo de Levaduras (AGL2013-47300-C3-2-R - Equipo Trabajo (Solicitud))
    • Evaluación de la Calidad y Seguridad de una Nueva Bebida Obtenida a partir de Fresa no apta para Comercialización (AGL2010-22152-C03-01 - Becario)

  • Ayuda a la investigación:
    • Incentivo al Grupo de Investigación AGR-167 (2017/AGR-167 - Investigador)

Cobertura de la base de datos de proyectos, véase aqui


Publicaciones:

Libros
Hornedo Ortega, Ruth:
Blueberry anthocyanins: profile, metabolism, and biological activity. New York. Nova Science Publishers. 2021. 157-198

Capítulos en Libros
Hornedo Ortega, Ruth, González Centeno , Maria Reyes, Chira , Kleopatra, Jourdes, Michaël, Teissedre , Pierre Louis:
Phenolic Compounds of Grapes and Wines: Key Compounds and Implications in Sensory Perception. Pag. 1-26. En: Chemistry and Biochemistry of Winemaking, Wine Stabilization and Aging. InTechOpen. 2021. ISBN 978-1-83962-576-3

Hornedo Ortega, Ruth, Catanescu , Giorgiana M, García Parrilla, Mª del Carmen, Troncoso Gonzalez, Ana Mª, Cerezo Lopez, Ana Belen:
Blueberry anthocyanins: profile, metabolism, and biological activity. Pag. 157-198. En: Blueberries. Nutrition, Consumption and Health. New York. Nova Science Publishers. 2021. ISBN 978-1-53619-646-7

Catanescu , Giorgiana M, Bodea, Iona M, Pop , Carmen R, Hornedo Ortega, Ruth, García Parrilla, Mª del Carmen, et. al.:
Effect of processing on the bioactivity of blueberries anthocyanins. Pag. 1-98. En: Blueberries. Nutrition, Consumption and Health. New York. Nova Science Publishers. 2021. ISBN 978-1-53619-646-7

Hornedo Ortega, Ruth, Martinez de Pablos, Rocio, Cerezo Lopez, Ana Belen, Richard , Tristan, García Parrilla, Mª del Carmen, et. al.:
Microglia-mediated neuroinflammation and Mediterranean diet. Pag. 347-356. En: The Mediterranean Diet. An Evidence-Based Approach. Philadelphia, . Agencia de los Estados Unidos para el Desarrollo Internacional (USAID) e Instituto para la Seguridad y la Democracia, A.C. (Insyde). Elsevier. 2020. ISBN 9780128186497

Publicaciones en Revistas
Aja Pérez, Iris, Krisa , Stephanie, Hornedo Ortega, Ruth, Ruiz Larrea, María Begoña, Ruiz Sanz, Jose Ignacio, et. al.:
Stilbenes at Low Micromolar Concentrations Mitigate the NO, TNF-¿, IL-1ß and ROS Production in LPS-Stimulated Murine Macrophages. En: Journal of Biologically Active Products from Nature. 2021. Vol. 11. Núm. 3. Pag. 212-222. 10.1080/22311866.2021.1923571

Benbouguerra , Nawel, Valls Fonayet , Josep, Krisa, Stephanie, Garcia, François, Saucier, Cédric, et. al.:
Polyphenolic Characterization of Merlot, Tannat and Syrah Skin Extracts at Different Degrees of Maturity and Anti-Inflammatory Potential in RAW264.7 Cells. En: Foods : Open Access Journal. 2021. Vol. 10. Núm. 541. Pag. 1-14. 10.3390/foods10030541

Benbouguerra , Nawel, Hornedo Ortega, Ruth, Garcia , François, El Khawand , Toni, Saucier , Cédric, et. al.:
Review/Reseña: Stilbenes in grape berries and wine and their potential role as anti-obesity agents: a review. En: Trends in Food Science & Technology. 2021. Vol. 112. Pag. 362-381. 10.1016/j.tifs.2021.03.060

Gallardo, Marta, Hornedo Ortega, Ruth, Alonso Bellido, Isabel M., Rodríguez Gómez, José A., Troncoso Gonzalez, Ana Mª, et. al.:
Hydroxytyrosol Decreases LPS- and ¿-Synuclein-Induced Microglial Activation In Vitro. En: Antioxidants. 2020. Vol. 9. Núm. 36. Pag. 362-18. https://doi.org/10.3390/antiox9010036

El Khawand , Toni, Valls Fonayet , Josep, Da Costa , Gregory, Hornedo Ortega, Ruth, Jourdes, Michael, et. al.:
Resveratrol transformation in red wine after treatment. En: Food Research International. 2020. Vol. 132. Núm. 109068

Cerezo Lopez, Ana Belen, C¿Tunescu, Giorgiana, Martínez¿Pais González, Mercedes, Hornedo Ortega, Ruth, Pop, Carmen R., et. al.:
Anthocyanins in Blueberries Grown in Hot Climate Exert Strong Antioxidant Activity and May Be Effective against Urinary Tract Bacteria. En: Antioxidants. 2020. Vol. 9. Núm. 478. Pag. 1-22. 10.3390/antiox9060478

Ubeda, Cristina, Cerezo Lopez, Ana Belen, Hornedo Ortega, Ruth, García Parrilla, Mª del Carmen, Troncoso Gonzalez, Ana Mª:
Chemical hazards in grapes and wine, climate change and challenges to face. En: Food Chemistry. 2020. Vol. 314. Núm. 126222. Pag. 1-10. https://doi.org/10.1016/j.foodchem.2020.126222

Dudoit , Auriane, Benbouguerra, Nawel, Richard , Tristan, Hornedo Ortega, Ruth, Valls Fonayet , Josep, et. al.:
¿-Glucosidase Inhibitory Activity of Tannat Grape Phenolic Extracts in Relation to Their Ripening Stages. En: Biomolecules. 2020. Vol. 10. Núm. 1088. Pag. 1-18. 10.3390/biom10081088

Cerezo Lopez, Ana Belen, Labrador, Maria, Gutierrez, Andres, Hornedo Ortega, Ruth, Troncoso Gonzalez, Ana Mª, et. al.:
Anti-VEGF Signalling Mechanism in HUVECs by Melatonin, Serotonin, Hydroxytyrosol and Other Bioactive Compounds. En: Nutrients. 2019. Vol. 11. Núm. 10. 10.3390/nu11102421

Gallardo, Marta, Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Melatonin, protocatechuic acid and hydroxytyrosol effects on vitagenes system against alpha-synuclein toxicity. En: Food and Chemical Toxicology. 2019. Vol. 134. Núm. 110817. Pag. 2421-11. 10.1016/j.fct.2019.110817

Wauquier , Fabien, Mevel , Elsa, Krisa , Stéphanie, Richard, Tristan, Valls, Josep, et. al.:
Chondroprotective Properties of Human-Enriched Serum Following Polyphenol Extract Absorption: Results from an Exploratory Clinical Trial. En: Nutrients. 2019. Vol. 11. Núm. 3071. 10.3390/nu11123071

Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Martinez de Pablos, Rocio, Krisa, Stephanie, Richard, Tristan, et. al.:
Phenolic Compounds Characteristic of the Mediterranean Diet in Mitigating Microglia-Mediated Neuroinflammation. En: Frontiers In Cellular Neuroscience. 2018. Vol. 12. 10.3389/fncel.2018.00373

Hornedo Ortega, Ruth, Da Costa , Grégory, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, Richard, Tristan, et. al.:
In vitro effects of serotonin, melatonin and other related indole compounds on amyloid ß kinetics and neuroprotection. En: Molecular Nutrition & Food Research. 2018. Vol. 62. Núm. 3. 10.1002/mnfr.201700383

Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Protective effects of hydrxytyrosol against alpha-synuclein toxicity on PC12 cells and fibril formation. En: Food and Chemical Toxicology. 2018. Vol. 120. Pag. 41-49. 10.1016/j.fct.2018.06.059

Courtois, Arnaud, Atgié, Claude, Marchal , Axel, Hornedo Ortega, Ruth, Lapèze, Caroline, et. al.:
Tissular distribution and metabolism of e-viniferin, a resveratrol dimer, after intraperitoneal injection in rat. En: Nutrients. 2018. Vol. 10(11). Núm. 1660

Cerezo Lopez, Ana Belen, Hornedo Ortega, Ruth, Alvarez Fernández, María Antonia, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Inhibition of VEGF-Induced VEGFR-2 Activation and HUVEC Migration by Melatonin and Other Bioactive Indolic Compounds. En: Nutrients. 2017. Vol. 9. Núm. 249. Pag. 1-17. 10.3390/nu9030249

Hornedo Ortega, Ruth, Alvarez Fernández, María Antonia, Cerezo Lopez, Ana Belen, García García, Isidoro, Troncoso Gonzalez, Ana Mª, et. al.:
Influence of Fermentation Process on the Anthocyanin Composition of Wine and Vinegar Elaborated from Strawberry. En: Journal of Food Science. 2017. Vol. 82. Pag. 364-372. 10.1111/1750-3841.13624

Cerezo Lopez, Ana Belen, Leal, Angela, Alvarez Fernández, María Antonia, Hornedo Ortega, Ruth, Troncoso Gonzalez, Ana Mª, et. al.:
Quality control and determination of melatonin in food supplements. En: Journal of Food Composition and Analysis. 2016. Núm. 45. Pag. 80-86. http://dx.doi.org/10.1016/j.jfca.2015.09.013

Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen, Mas, Albert:
Review/Reseña: Melatonin and other tryptophan metabolites produced by yeasts: implications in cardiovascular and neurodegenerative diseases. En: Frontiers in Microbiology. 2016. Vol. 6. Núm. 1565. Pag. 1-7. 10.3389/fmicb.2015.01565

Hornedo Ortega, Ruth, Alvarez Fernández, María Antonia, Cerezo Lopez, Ana Belen, Richard, Tristan, Troncoso Gonzalez, Ana Mª, et. al.:
Protocatechuic acid: inhibition of fibril formation, destabilization of pre-formed fibrils of Amyloid-ß and ¿-Synuclein, and neuroprotection. En: Journal of Agricultural and Food Chemistry. 2016. Vol. 64. Núm. 41. Pag. 7722-7732. 10.1021/acs.jafc.6b03217

Hornedo Ortega, Ruth, Krisa, Stephanie, García Parrilla, Mª del Carmen, Richard, Tristan:
Effects of gluconic and alcoholic fermentation on anthocyanin composition and antioxidant activity of beverages made from strawberry. En: LWT-Food Science and Technology. 2016. Vol. 69. Pag. 382-389. 10.1016/j.lwt.2016.01.070

Hornedo Ortega, Ruth, Alvarez Fernández, María Antonia, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Influence of storage conditions on the anthocyanin profile and colour of an innovative beverage elaborated by gluconic fermentation of strawberry. En: Journal of Functional Foods. 2016. Vol. 23. Núm. 0. Pag. 198-209. 10.1111/1750-3841.13624

Alvarez Fernández, María Antonia, Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Determination of Nonanthocyanin Phenolic Compounds Using High-Resolution Mass Spectrometry (UHPLC-Orbitrap-MS/MS) and Impact od Storage Conditions in a Beverage Made from Strawberry by Fermentation. En: Journal of Agricultural and Food Chemistry. 2016. Núm. 64. Pag. 1367-1376. 10.1021/acs.jafc.5b05617

Callejón Fernández, Raquel Mª, Rodriguez Naranjo, Mª Isabel, Ubeda, Cristina, Hornedo Ortega, Ruth, García Parrilla, Mª del Carmen, et. al.:
Reported Foodborne Outbreaks Due to Fresh Produce in the United States and European Union: Trends and Causes. En: Foodborne Pathogens and Disease. 2015. Vol. 12. Núm. 1. Pag. 32-38. 10.1089/fpd.2014.1821

Alvarez Fernández, María Antonia, Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Effects of the strawberry (Fragaria ananassa) purée elaboration process on non-anthocyanin phenolic composition and antioxidant activity. En: Food Chemistry. 2014. Núm. 164. Pag. 104-112. 10.1016

Alvarez Fernández, María Antonia, Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Non-anthocyanin phenolic compounds and antioxidant activity of beverages obtained by gluconic fermentation of strawberry. En: Innovative Food Science and Emerging Technologies. 2014. Núm. 26. Pag. 469-481. 10.1016/j.ifset.2014.08.001

Cerezo Lopez, Ana Belen, Alvarez Fernández, María Antonia, Hornedo Ortega, Ruth, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Phenolic Composition of Vinegars over an Accelerated Aging Process Using Different Wood Species (Acacia, Cherry, Chestnut, and Oak): Effect of Wood Toasting. En: Journal of Agricultural and Food Chemistry. 2014. Vol. 62. Pag. 4369-4376

Hornedo Ortega, Ruth:
Meeting-Abstract: Experiencias del Profesorado Novel del Área de Toxicología en el Programa de Formación de la Universidad de Sevilla. En: Revista de Toxicología. 2013. Vol. 30

Aportaciones a Congresos
Hornedo Ortega, Ruth, Jourdes, Michaël, Da Costa, Gregory, Courtois , Arnaud, Gabaston, Julien, et. al.:
Gnetol and oxyresveratrol glucuronide metabolites: Chemical production, structural identification, metabolism by human and rat liver fractions and in vitro anti-inflammatory properties. Ponencia en Congreso. XXX International Conference of Polyphenols. Turku (Finlandia). 2021

Alonso, Isabel Maria, Gallardo, Marta, Hornedo Ortega, Ruth, Rodriguez Gómez, Jose Antonio, Troncoso Gonzalez, Ana Mª, et. al.:
Hydroxytyrosol decreases LPS and a-synuclein-induced microglial activation in vitro. Comunicación en congreso. FENS 2020 Virtual Forum. - Londres, Reino Unido. Virtual. 2020

Gallardo, Marta, Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Joined effect of hydroxytyrosol, protocatechuic acid and melatonin on alpha-synuclein aggregation and vitagenes expression in PC12 cells. Poster en Congreso. 13th European Nutrition Conference, Federation of European Nutrition Societies. Dublin. 2019

Gallardo, Marta, Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, García Parrilla, Mª del Carmen, Troncoso Gonzalez, Ana Mª:
Efecto de melatonina, ácido protocatéquico e hidroxitirosol en el sistema de vitagenes frente a la toxicidad de la alfa sinucleína. Comunicación en congreso. II Congreso de jóvenes investigadores en ciencias agroalimentarias. Almería. 2019

Benbouguerra, Nawel, Zerbib, M, Hornedo Ortega, Ruth, Richard, Tristan, Garcia, François, et. al.:
Evolution of antioxidant properties of seeds and skins extracts during ripening of Vitis Vinifera berries. Poster en Congreso. 11th International Symposium of OEnology - 11th edition In Vino Analytica Scientia. Burdeos (Francia). 2019

Daniault , Justine, Valls, Josep, Hornedo Ortega, Ruth, Gougeon , Louis, Renouf , Elodie, et. al.:
Characterization and cytoprotective effects of polyphenolic extracts of wine on neuronal cells. Poster en Congreso. 11th International Symposium of OEnology - 11th edition In Vino Analytica Scientia. Burdeos (Francia). 2019

Benbouguerra, Nawel, Zerbib , M, Hornedo Ortega, Ruth, Richard , Tristan, Saucier , Cédric, et. al.:
Electroquemical characterization of grape extracts of seeds and skins during ripening of Vitis Vinifera grapes for antioxidant properties determination. Poster en Congreso. 11th International Symposium of OEnology - 11th edition In Vino Analytica Scientia. Burdeos (Francia). 2019

Aja Perez, Iris, Krisa, Stephanie, Hornedo Ortega, Ruth, Ruiz Snaz, Jose Ignacio, Richard , Tristan, et. al.:
Stilbenes from Vitis Vinifera: phytochemical analysis and study of their anti-inflammatory effects in LPS-stimulated macrophages. Poster en Congreso. 11th International Symposium of OEnology - 11th edition In Vino Analytica Scientia. Burdeos (Francia). 2019

Hornedo Ortega, Ruth, Gallardo, Marta, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Combined neuroprotective effects of melatonin, protocatechuic acid and hydroxytyrosol on alpha-synuclein fibrils formation. Poster en Congreso. American Society for Nutrition's Annual Meeting. Nutrition 201. Boston, MA. 2018

Troncoso Gonzalez, Ana Mª, Marquez , Enrique, Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, García Parrilla, Mª del Carmen:
Impact of a Nutrition App in improving eating habits. Poster en Congreso. IV World Congress of Public Health Nutrition y XI Congress of the Spanish Society of Community Nutrition. Madrid. 2018

Garcia, Manon, Hornedo Ortega, Ruth, El Khawand , Toni, Krisa, Stephanie, Sauvant , Patrick, et. al.:
Effect of encapsulation of e-viniferin, a resveratrol dimer, stability and cytotoxicity on Caco2 cells. Ponencia en Congreso. French-Spanish Meeting of the Conferences on Trans-Pyrenean Investigations in Obesity and Diabetes. Toulouse. 2018

Espinosa Oliva, Ana Maria, González Miranda, Ezequiel, Tayara, Khadija, Hornedo Ortega, Ruth, Herrera Carmona, Antonio Jose, et. al.:
Involvement of caspase-8 in microglial activation mediated by B-amyloid. Poster en Congreso. XIII Euroepan Meeting on Glial Cells in Health and Disease. Edinburgo. 2017

Cerezo Lopez, Ana Belen, Alvarez Fernández, María Antonia, Hornedo Ortega, Ruth, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Melatonin and other indolic related compounds inhibit VEGFinduced VEGFR-2 activation and HUVEC migration in vitro. Comunicación en congreso. The 1st International Conference of Food Bioactives & Health. Institute of Food Research, Norwich, Reino Unido. 2016

Hornedo Ortega, Ruth, García Parrilla, Mª del Carmen, Troncoso Gonzalez, Ana Mª:
Inhibition of aggregation of beta amyloid by melatonin and derived indolic compounds. Poster en Congreso. 12th European Nutrition Conference 2015. Berlin, Germany. 2015

Hornedo Ortega, Ruth, Krisa, Sthephanie, Alvarez Fernández, María Antonia, Richard, Tristan, Troncoso Gonzalez, Ana Mª, et. al.:
Bebidas obtenidas por fermentación glucónica de fresa: efectos neuroprotectores en células PC12. Comunicación en congreso. III Congreso FESNAD. Sevilla, España. 2015

Maisanaba Hernández, Sara, Llana Ruiz-Cabello, María, Hornedo Ortega, Ruth, Moreno Navarro, Isabel Maria:
Experiencias del Profesorado Novel del Área de Toxicología en el Programa de Formación de la Universidad de Sevilla. Poster en Congreso. XX Congreso Español de Toxicología y IV Iberoamericano. - Salamanca, España. 2013

Alvarez Fernández, María Antonia, Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Identification of phenolic compounds by LC-MS in drinks obtained by gluconic fermentation from strawberry (Fragaria ananassa). Comunicación en congreso. IUNS 20th International Congress of Nutrition. Palacio de Exposiciones y Congresos de Granada, Granada, España. 2013

Cerezo Lopez, Ana Belen, Alvarez Fernández, María Antonia, Hornedo Ortega, Ruth, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Cambios en la composición fenólica de vinagres de vino envejecidos en contacto con maderas tostadas y sin tostar de acacia, castaño, cerezo y roble. Comunicación en congreso. Nuevas perspectivas en investigación vitivinicola. - Madrid, España. 2013

Alvarez Fernández, María Antonia, Hornedo Ortega, Ruth, Cerezo Lopez, Ana Belen, Troncoso Gonzalez, Ana Mª, García Parrilla, Mª del Carmen:
Phenolic profile of beverages obtained by gluconic fermentation of strawberry. Comunicación en congreso. VI International Conference on Pholyphenols and Health. Buenos Aires, ARGENTINA. 2013

García Parrilla, Mª del Carmen, Alvarez Fernández, María Antonia, Cerezo Lopez, Ana Belen, Hornedo Ortega, Ruth, Troncoso Gonzalez, Ana Mª:
Phenolic characterization and antioxidant activity of strawberry (Fragaria ananassa) puree. Comunicación en congreso. 20th International Congress of Nutrition. 2013

Hornedo Ortega, Ruth:
Impact of a Nutrition App in improving eating habits. Poster en Congreso

Vicerrectorado de Investigación. Universidad de Sevilla. Pabellón de Brasil. Paseo de las Delicias s/n. Sevilla