Universidad de Sevilla

Vicerrectorado de Investigación

Ficha personal - Rebeca Mejías Estévez


Rebeca Mejías Estévez
Telefono: 95.501.26.44/45
Email: Solicitar correo
Perfil en ORCID: 0000-0003-1936-7219
Perfil en WOS: B-4696-2008

Grupo de Investigación: CTS-630 Trastornos del Movimiento
Departamento/Unidad: Fisiología
Situación profesional: Profesor Contratado Doctor

Participa en los siguientes proyectos/ayudas en la US:

  • Proyecto de investigación:
    • Plasticidad del sistema oculomotor en respuesta a la lesión: papel de los factores neurotróficos y de las células progenitoras (P20_00529 - Equipo de Investigación)
    • Lesión y Regeneración: una Evaluación Neurotrófica de la Función y Plasticidad Oculomotora (PGC2018-094654-B-I00 - Equipo de Investigación)
    • Estrategias Reparativas en el Snc Tras la Lesión: Administración del Factor de Crecimiento del Endotelio Vascular (Vegf) e Implante de Progenitores Neurales (BFU2015-64515-P - Equipo de Investigación)
    • Sensibilidad al oxígeno y neurodegeneración (SAF2006-08311 - Otro Investigador)

Cobertura de la base de datos de proyectos, véase aqui


Publicaciones:

Publicaciones en Revistas
Gonzalez-Serna Martín, Manuel Alejandro, Vázquez Carretero, María Dolores, Garcia Miranda, Pablo, Cano Rodríguez, Mercedes, Calonge Castrillo, Mª Luisa, et. al.:
Un MinuTikTok de Fisiología. En: RESCIFAR: Revista Española de Ciencias Farmacéuticas. 2024. Vol. 1. Núm. 1. Pag. 11-17

Fontan Lozano, Angela, Morcuende, Sara, Davis López de Carrizosa, María América, Benitez Temiño, Beatriz, Mejias Estevez, Rebeca Maria, et. al.:
To become or not to become tumorigenic: subventricular zone versus hippocampal neural stem cells. En: Frontiers in Oncology. 2020. Vol. 27. Núm. 10. Pag. 602217-602217. doi.org/10.3389/fonc.2020.602217

Mejias Estevez, Rebeca Maria, Chiu, Shu Ling, Han, Mei, Rose, Rebecca, Gil Infante, Ana, et. al.:
Purkinje Cell-Specific Grip1/2 Knockout Mice Show Increased Repetitive Self-Grooming and Enhanced mGluR5 Signaling in Cerebellum. En: Neurobiology of Disease. 2019. Vol. 132. https://www.sciencedirect.com/science/article/pii/S0969996119302773?via%3Dihub

Han, Mei, Mejias Estevez, Rebeca Maria, Chiu, Shu Ling, Rose, Rebecca, Adamczyk, Abby, et. al.:
Mice lacking GRIP1/2 show increased social interactions and enhanced phosphorylation of GluA2-S880. En: Behavioural Brain Research. 2017. Vol. 321. Pag. 176-184

Macdonald, Elizabeth M, Andrés Mateos, Eva, Mejias Estevez, Rebeca Maria, Simmers, Jessica L, Mi, Ruifa, et. al.:
Denervation atrophy is independent from Akt and mTOR activation and responds differently than disuse atrophy to myostatin inhibition. En: Disease Models & Mechanisms. 2014. Vol. 7. Pag. 471-481

Mejias Estevez, Rebeca Maria:
Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy. 2013. Vol. 5. Pag. 80-91

Andrés Mateos, Eva, Brinkmeier, Heinrich, Burks, Tyesha N, Mejias Estevez, Rebeca Maria, Files, Daniel C, et. al.:
Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy. En: EMBO Molecular Medicine. 2013. Vol. 5. Pag. 80-91

Xu, Ran, Andrés Mateos, Eva, Mejias Estevez, Rebeca Maria, Macdonald , Elizabeth M, Leinwand, Leslie, et. al.:
Hibernating squirrels activates endurance exercise pathway despite prolonged immobilization and starvation. En: Experimental Neurology. 2013. Vol. 247. Pag. 392-401

Adamczyk, Abby, Mejias Estevez, Rebeca Maria, Takamiya, Kogo, Yocum, Jennifer, Krasnova, Irina N, et. al.:
GluA3-deficiency in mice is associated with increased social and aggressive behavior and elevated dopamine in striatum. En: Behavioural Brain Research. 2012. Vol. 229. Pag. 265-272

Andrés Mateos, Eva, Mejias Estevez, Rebeca Maria, Soleimani , Arshia, Lin, Brian M, Burks, Tyesha N, et. al.:
Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels. En: PLoS One. 2012. Vol. 7

Mejias Estevez, Rebeca Maria, Adamczyk, Abby, Anggono, Victor, Niranjan, Tejasvi, Thomas, Gareth M, et. al.:
Gain-of-function GRIP1 variants alter GluA2 recycling and surface distribution in patients with Autism. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2011. Vol. 108. Pag. 4920-4925

Burks, Tyesha N, Andrés Mateos, Eva, Marx, Ruth, Mejias Estevez, Rebeca Maria, Van Erp, Christel, et. al.:
Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia. En: Science Translational Medicine. 2011. Vol. 3

Romero Ruiz, Antonio, Mejias Estevez, Rebeca Maria, Diaz Martin, Juan, Lopez Barneo, Jose, Gao Chen, Lin:
Mesencephalic and striatal protein profiles in mice over-expressing glucose-6-phosphate dehydrogenase in dopaminergic neurons. En: Journal of Proteomics. 2010. Vol. 73. Núm. 9. Pag. 1747-1757

Andrés Mateos, Eva, Mejias Estevez, Rebeca Maria, Sasaki, Masayuki, Li, Xiaojie, Lin, Brian M, et. al.:
Hypersensitivity in LRRK2 Knock-out Mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). En: The Journal of Neuroscience. 2009. Vol. 29. Pag. 15846-15850

Gao Chen, Lin, Díaz Corrales, Francisco Javier, Carrillo Garcia, Fatima, Carballo Cordero, Manuel, Palomino García, Alfredo, et. al.:
Prevalence and clinical features of LRRK2 mutations in patients with Parkinson's disease in southern Spain. En: European Journal of Neurology. 2009. Vol. 16. Núm. 8. Pag. 957-960

Gao Chen, Lin, Mir Rivera, Pablo, Díaz Corrales, Francisco Javier, Mejias Estevez, Rebeca Maria, Carrillo Garcia, Fatima, et. al.:
Glucose-6-phosphate dehydrogenase activity in Parkinson's disease. En: Journal of Neurology. 2008. Vol. 255. Núm. 11. Pag. 1850-1851

Garcia Fernandez, Maria, Mejias Estevez, Rebeca Maria, Lopez Barneo, Jose:
Developmental Changes of Chromaffin Cell Secretory Response to Hypoxia Studied in Thin Adrenal Slices. En: Pflugers Archiv: European Journal of Physiology. 2007. Vol. 454. Núm. 1. Pag. 93-100

Mir, Pablo, Díaz Corrales, Francisco Javier, Mejias Estevez, Rebeca Maria, Carrillo Garcia, Fatima, Vime, Pablo, et. al.:
Meeting-Abstract: Glucose-6-phosphate dehydrogenase in the peripheral blood of patients with Parkinson¿s disease. En: Movement disorders. 2007. Vol. 22

Mir, Pablo, Díaz Corrales, Francisco Javier, Carrillo Garcia, Fatima, Carballo Cordero, Manuel, Palomino García, Alfredo, et. al.:
Meeting-Abstract: LRRK2 mutations in patients with Parkinson's disease in southern Spain. En: Movement disorders. 2007. Vol. 22

Mejias, R, Mejias Estevez, Rebeca Maria, Villadiego Luque, Francisco Javier, Pintado Sanjuan, Carmelo Oscar, Pintado, O.C., et. al.:
Neuroprotection by Transgenic Expression of Glucose-6-Phosphate Dehydrogenase in Dopaminergic Nigrostriatal Neurons of Mice. En: Advances in Experimental Medicine and Biology. 2006. Vol. 26. Núm. 17. Pag. 4500-4508

Gao, Lin, Gao Chen, Lin, Mejias Estevez, Rebeca Maria, Echevarria Irusta, Miriam, Lopez Barneo, Jose, et. al.:
Induction of the Glucose-6-Phosphate Dehydrogenase Gene Expression by Chronic Hypoxia in Pc12 Cells. En: FEBS Letters. 2004. Vol. 569. Núm. 1-3. Pag. 256-260

Limón Mirón, Maria del Carmen, Limón, Maria del Carmen, Chacón, M. R., Mejias Estevez, Rebeca Maria, Mejias, R, et. al.:
Increased Antifungal and Chitinase Specific Activities of Trichoderma Harzianum CECT 2413 by Addition of a Cellulose Binding Domain. En: Applied Microbiology and Biotechnology. 2004. Vol. 64. Núm. 5. Pag. 675-685

Dana Jiménez, Mª de las Mercedes, Limón Mirón, Maria del Carmen, Mejias Estevez, Rebeca Maria, Mach, R.L., Benitez Fernandez, Concepcion Tahia, et. al.:
Regulation of Chitinase 33 (Chit33) Gene Expression in Trichoderma Harzianum. En: Current Genetics. 2001. Vol. 38. Núm. 6. Pag. 335-342

Aportaciones a Congresos
Ives, M., Fontes, M., Mejias Estevez, Rebeca Maria, Chou, S., Hegarty, A., et. al.:
Abcam strategy to support Parkinson¿s disease research. Poster en Congreso. The Milner Therapeutics Symposium. . Cambridge, . Cambridge, Reino Unido. 2019

Dornblut, C., Mejias Estevez, Rebeca Maria, Ives, M., Fontes, M., Chou, S., et. al.:
Abcam Strategy to Support Parkinson¿s disease Research. Poster en Congreso. Congreso Nacional de la Sociedad Española de Neurociencia. Santigo de Compostela. España. 2019

Mejias Estevez, Rebeca Maria:
A study of hypothalamus in germ-free mice. Conferencia en Seminario no publicada. In-depth Seminars. Norwich, Reino Unido. 2018

Mejias Estevez, Rebeca Maria, Benitez Temiño, Beatriz, Morcuende, Sara, Rodríguez Matarredona, Esperanza, G. Hernández, Rosendo, et. al.:
Increased interest in science and physiology among students of secondary education after the outreach activity: ¿from DNA to functional tissue¿. Comunicación en congreso. XXXIX Congress of the Spanish Society of Physiological Sciences (SECF). Cádiz, España. 2018

Rodríguez Gotor, Juan José, Adamczyk, Abby, Krasnova, Irina, Cadet, Jean Lud, Fuller, William, et. al.:
Proteomic and stereological studies in the striatum of a mouse deficient in palmitoyl-acyltransferase DHHC15. Poster en Congreso. Barcelona Young Neuroscientists Symposium 2018. Barcelona. 2018

Mejias Estevez, Rebeca Maria, Adamczyk, Abby, Rodríguez Gotor, Juan José, Niwa, Minae, Krasnova, Irina, et. al.:
DHHC15-mediated palmitoylation modulates striatal dopamine levels and spontaneous locomotion. Poster en Congreso. Acylation of intracellular and secreted proteins: mechanisms and functional outcomes. Brighton. 2018

Rodríguez Gotor, Juan José, Fuller, William, Wang, Tao, Mejias Estevez, Rebeca Maria:
Study of the striatal palmitome in a mouse deficient in the palmitoyl acyltransferase DHHC15. Poster en Congreso. Acylation of intracellular and secreted proteins: mechanisms and functional outcomes. Brighton. 2018

Gil Infante, Ana, Rodríguez Gotor, Juan José, Mejias Estevez, Rebeca Maria:
Palmitoylation of proteins related with Parkinson Disease. Poster en Congreso. Barcelona Young Neuroscientists Symposium. . Barcelona. 2017

Mejias Estevez, Rebeca Maria, Chiu, Shu Ling, Han, Mei, Rose, Rebecca, Huganir, Richard L, et. al.:
Mice with Purkinje Cell-specific deletion of Grip1/2 Show Increased Repetitive Grooming Behaviors. Poster en Congreso. 17 Congreso Nacional de la SENC Sociedad Española de Neurociencia. Alicante. 2017

Gil Infante, Ana, Rodríguez Gotor, Juan José, Cabrera Justo, Manuel, Mejias Estevez, Rebeca Maria:
Study of the palmitoylation of proteins related to Parkinson¿s Disease. Poster en Congreso. Barcelona Young Neuroscientists Symposium. . Barcelona. 2017

Rodríguez Gotor, Juan José, Cabrera Justo, Manuel, Wang, Tao, Mejias Estevez, Rebeca Maria:
Study of nigrostriatal and mesolimbic pathways in a mouse deficient in palmitoyl-acyltransferase DHHC15. Poster en Congreso. Barcelona Young Neuroscientists Symposium. . Barcelona. 2017

Mejias Estevez, Rebeca Maria:
Modelos animales y deficiencias sociales en el autismo. Conferencia en Seminario no publicada. Seminarios del Departamento de Psicología Evolutiva y de la Educación, Facultad de Psicología, Universidad de Sevilla. Facultad de Psicología, Universidad de Sevilla. 2017

Mejias Estevez, Rebeca Maria:
DHHC15 palmitoylation modulates striatal dopamine system. Conferencia en Seminario no publicada. Seminarios del Programa de Neurociencias. Sevilla. 2016

Han, Mei, Mejias Estevez, Rebeca Maria, Rose, Rebecca, Chiu, Shu Ling, Adamczyk, Abby, et. al.:
Increased social behaviors and GluA2 phosphorylation in mice-lacking glutamate receptor interacting proteins. Poster en Congreso. Annual Meeting. Society for Neuroscienc. Chicago (EEUU). 2015

Mejias Estevez, Rebeca Maria, Adamczyk , Abby, Niwa, Minae, Krasnova, Irina N, Thomas, Gareth M, et. al.:
DHHC15-mediated palmitoylation modulates striatal dopamine levels and spontaneous locomotion. Poster en Congreso. 45th Annual Meeting of the Society for Neuroscience. Chicago, EEUU. 2015

Mejias Estevez, Rebeca Maria, Adamczyk, Abby, Niwa, Minae, Krasnova, Irina N, Thomas, Gareth M, et. al.:
DHHC15-mediated palmitoylation modulates striatal dopamine levels and spontaneous locomotion. Poster en Congreso. XVI Congreso de la Sociedad Española de Neurociencia. Granada, España. 2015

Han, Mei, Mejias Estevez, Rebeca Maria, Huganir, Richard L, Wang, Tao:
Enhancing AMPA signaling improves sociability in an autism mouse model. Poster en Congreso. Annual Meeting of the Society for Neuroscience. Washington, Estados Unidos. 2014

Niranjan , Tejasvi S, Mejias Estevez, Rebeca Maria, Han, Mei, Adamczyk, Abby, Rose, Rebecca, et. al.:
GRIP2-mediated AMPA signaling defects contribute to autism social behavioral deficits. Poster en Congreso. Annual Meeting of the American Society of Human Genetics. California, California, California, San Diego; Estados Unidos de America. 2014

Mejias Estevez, Rebeca Maria, Chiu, Shu Ling, Han, Mei, Rose, Rebecca, Huganir, Richard L, et. al.:
Mice with Purkinje Cell-specific deletion of Grip1/2 Show Increased Repetitive Grooming Behaviors. Comunicación en congreso. Annual Meeting of the Society for Neuroscience. Washington, Estados Unidos. 2014

Mejias Estevez, Rebeca Maria, Adamczyk, Abby, Wang, Julia, Thomas, Gareth M, Helling , Tiffany D, et. al.:
Increased ambulatory activities in mice lacking palmitoyltransferase DHHC15. Poster en Congreso. Society for Neuroscience Meeting. California, San Diego; Estados Unidos de America. 2013

Simmers, Jessica L, Chaerkady , Raghothama, Finanger Hedderick , Erika, Marx, Ruth, Mejias Estevez, Rebeca Maria, et. al.:
Mislocalization of nNOS alters the interactions between nNOS and proteins involved with muscle contraction in steroid-induced myopathy. Poster en Congreso. 17th International Congress of the World Muscle Society Congress. Perth, Australia. 2012

Burks, Tyesha N, Andrés Mateos, Eva, Marx, Ruth, Simmers, Jessica L, Mejias Estevez, Rebeca Maria, et. al.:
Angiotensin II type 1 receptor blockade protects against disuse atrophy in sarcopenic mice. Poster en Jornada. 5th Annual Research on Aging Showcase. Baltimore, BALTIIMORE, MARYLAND, EEUU. 2012

Macdonald , Elizabeth M, Simmers, Jessica L, Andrés Mateos, Eva, Mejias Estevez, Rebeca Maria, Lee, Se Jin, et. al.:
The myostatin inhibitor ActIIb rescues atrophy and protects muscle growth signaling pathways in immobilization but not denervation. Poster en Congreso. 17th International Congress of the World Muscle Society Congress. Perth, Australia. 2012

Mejias Estevez, Rebeca Maria:
Role of GRIP1 in autism. Conferencia en Seminario no publicada. Seminarios Mensuales del Centro de Esquizofrenia. Baltimore, BALTIIMORE, MARYLAND, EEUU. 2012

Burks, Tyesha N, Andrés Mateos, Eva, Marx, Ruth, Mejias Estevez, Rebeca Maria, Walston, Jeremy D, et. al.:
Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia. Poster en Congreso. 64th Annual Scientific Meeting of the Gerontological Society of America. 2011

Rose, Rebecca, Mejias Estevez, Rebeca Maria, Adamczyk, Abby, Huganir, Richard L, Wang, Tao:
Increased sociability and social interaction in mice lacking glutamate receptor interacting proteins. Poster en Congreso. 12th International Congress of Human Genetics. Montreal, Canadá. 2011

Rose, Rebecca, Mejias Estevez, Rebeca Maria, Adamczyk, Abby, Huganir, Richard L, Wang, Tao:
Mice lacking glutamate receptor interacting proteins show an increase in sociability and social interaction. Poster en Congreso. Cell Symposia: Autism Spectrum Disorders: From Mechanisms to Therapies. Arlington, VA, EEUU. 2011

Mir Rivera, Pablo, Gao Chen, Lin, Díaz Corrales, Francisco Javier, Carrillo Garcia, Fatima, Carballo Cordero, Manuel, et. al.:
LRRK2 mutations in patients with Parkinson's disease in Southern Spain. Poster en Congreso. 11th International Congress of Parkinson¿S Disease and Movement Disorders. Istanbul, Turkey. 2007. Movement Disorders. S127. S127

Mir Rivera, Pablo, Gao Chen, Lin, Díaz Corrales, Francisco Javier, Mejias Estevez, Rebeca Maria, Vime, Pablo, et. al.:
Glucose-6-phosphate dehydrogenase in the peripheral blood of patients with Parkinson`s disease. Poster en Congreso. 11th International Congress of Parkinson¿S Disease and Movement Disorders. Istanbul, Turkey. 2007. Movement Disorders. S198. S199

Díaz Corrales, Francisco Javier, Gao Chen, Lin, Carrillo Garcia, Fatima, Carballo Cordero, Manuel, Diaz Martin, Juan, et. al.:
Prevalencia y características clínicas de la mutación LRRK2 en pacientes con enfermedad de Parkinson (EP) en el Sur de España. Comunicación en congreso. LIX Reunión de la Sociedad Española de Neurología. 2007. Neurologia. 647. 647

Limón Mirón, Maria del Carmen, Chacón Rodríguez, Mariola, Mejias Estevez, Rebeca Maria, Delgado, Jesús, Rincon Romero, Ana Maria, et. al.:
Increased Antifungal and Chitinase Specific Activities of Trichoderma Harzianum 2413 by Addition of a Cellulose Binding Domain. Poster en Congreso. European Conference on Fungal Genetics. Copenhagen (Dinamarca). 2004. 7th European Conference on Fungal Genetics. 198. 198

Mejias Estevez, Rebeca Maria, Villadiego Luque, Francisco Javier, Pintado Sanjuan, Carmelo Oscar, P, Vime, Toledo Aral, Juan José, et. al.:
Transgenic Mice Over-Expressing G6pd in Nitrostriatal Neurons: General Characteristics and Resistance to Mptp Toxicity. Comunicación en congreso. Workshop on Neuronal Degeneration and Novel Therapeutic Approaches in Parkinson's Disease. 2003. Workshop on Neuronal Degeneration and Novel Therapeutic Approaches in Parkinson's Disease. 54. 54

Chacón, M. R., Chacón Rodríguez, Mariola, Limón Mirón, Maria del Carmen, Mejias Estevez, Rebeca Maria, Delgado, Jesús, et. al.:
Aumento de Actividad de Quitinasas de T. Harzianum que Poseen un Dominio de Unión a Sustrato. Poster en Congreso. Congreso Nacional de Biotecnología 2002. 2002. Biotec 2002. 232. 232

Otras Publicaciones
Mejias Estevez, Rebeca Maria:
Blog en la revista Investigación y Ciencia: "El yin y el yang de la mente". Otras Publicaciones. 2015. Español. http://www.investigacionyciencia.es/blogs/psicologia-y-neurociencia/77/posts

Vicerrectorado de Investigación. Universidad de Sevilla. Pabellón de Brasil. Paseo de las Delicias s/n. Sevilla