Cintia Roodveldt
Telefono: 954467403
Email: Solicitar correo
Perfil en ORCID: 0000-0003-4124-8769
Perfil en WOS: I-9118-2014
Perfil en Scopus: 6508154705

Grupo de Investigación: Terapias Avanzadas en Inmunomodulacion y Neuroproteccion
Departamento/Unidad: Bioquímica Médica y Biología Molecular e Inmunología
Situación profesional: Profesor Titular de Universidad

Responsable de los siguientes proyectos/ayudas en la US:

• Proyecto de investigación:
  • Quinasas de señalización y mecanismos de inmunoregulación en esclerosis lateral amiotrófica (ELA) (PID2022-140838OB-I00)
  • Mecanismos moleculares de una proteína de la familia BET en la respuesta neuroinflamatoria asociada a proteinopatías neurodegenerativas (P20_01097)
  • Caracterización funcional y de los mecanismos de acción mediados por la kinasa de señalización MOK en la neuroinflamación asociada a la Esclerosis Lateral Amiotrófica (ELA) (2019/FARECES/CROODVELT)
  • Caracterización Funcional e Intervención de una Nueva Ruta de Señalización de la Neuroinflamación Mediada por Microglia en Esclerosis Lateral Amiotrófica (Ela) (RTI2018-098432-B-I00)
  • Caracterización funcional y de los mecanismos de acción mediados por MOK en la neuroinflamación asociada a proteinopatías neurodegenerativas: Esclerosis Lateral Amiotrófica (ELA) y Enfermedad de Parkinson (US-1265227)
  • Role and inmunotherapeutic potential of molecular chaperones in neurodegenerative amyloid disorders (RYC-2016-21372)
  
  
• Ayuda a la investigación:
  • Ayuda para estancia Estudio de la participación de la kinasa MOK en la respuesta inmunitaria de astrocitos y células T asociada a la inflamación. (PP2019-12150)
  
  
• Programa de Movilidad:
  • Modalidad B. Ayudas para la recualificación del profesorado universitario funcionario o contratado. Primer periodo (REC-B-22345-1)
  
  

Participa en los siguientes proyectos/ayudas en la US:

• Proyecto de investigación:
  • The molecular basis of human disease: from cell to organismal biology (SOL2024-31756 - Equipo de Investigación)
  • Estudio de la capacidad inmunoreguladora del péptido intestinal vasoactivo (VIP) sobre células madre derivadas de tejido adiposo (CMDA) en el modelo preclínico de esclerosis múltiple (PS09/02252 - Investigador)
  
  
• Contrato con empresas (Arts. 68/83 LOU):
  • Towards a therapeutic vaccine for Amyotrophic lateral sclerosis: ALSVac (2106/0013 - Investigador)
  • Diseño e implantación de Programas de I+D+I estratégicos en Terapia Génica, Celular y Nanomedicina. Área Desarrollo de la Producción Científica. Fundación Pública Andaluza Progreso y Salud. Consejería de Salud. Junta de Andalucía. (0669/0013 - Investigador)
  • Diseño e implantación de programas y proyectos de innovación e investigación biomédica del Sistema Sanitario Público de Andalucia (0014/0013 - Investigador)
  
  
• Ayuda a la investigación:
  • Unidad de Excelencia “María de Maeztu”. Centro Andaluz de Biología Molecular y Medicina Regenerativa (QUAL21 007 USE - Equipo de Investigación)
  • Incentivo al Grupo de Investigación CTS-677 (2017/CTS-677 - Investigador)
  • Incentivo al Grupo de Investigación CTS-677 (2011/CTS-677 - Investigador)
  • Incentivo al Grupo de Investigación CTS-677 (2010/CTS-677 - Investigador)
  • Ayuda a la Consolidación del Grupo de Investigación BIO-323 (2008/BIO-323 - Investigador)
  
  

Cobertura de la base de datos de proyectos, véase aqui

Publicaciones:

Otra participación en Libros

Roodveldt, Cintia (Editor/a), Outeiro, Tiago F (Editor/a), Braun, Janice e (Editor/a):
Molecular chaperones and Neurodegeneration. Basel, Switzerland. Frontiers in Neurology. 2017

Capítulos en Libros

Roodveldt, Cintia, Labrador Garrido, Adahir, Izquierdo, Guillermo, Fernández Montesinos, Rafael, Pozo Pérez, David:
Alpha-Synuclein and the Immune System in Parkinson's Disease. Pag. 57-76. En: Towards New Therapies for Parkinson's Disease (Ed. Intech, Vienna, Austria). Vienna, Austria. Intech - Open Access Publisher. 2011. ISBN 978-953-307-463-4

Labrador Garrido, Adahir, Bertoncini, Carlos W., Roodveldt, Cintia:
The Hsp70 Chaperone System in Parkinson's Disease. Pag. 221-246. En: Etiology and Pathophysiology of Parkinson's Disease (Ed. Intech, Vienna, Austria). Viena, Austria. Intech - Open Access Publisher. 2011. ISBN 978-953-307-462-7

Aharoni, a, Roodveldt, Cintia, Griffiths, Ad, Tawfik, Ds:
High-Throughput Screens and Selections of Enzyme Encoding Genes. Pag. 163-179. En: Enzyme Assays: High-Throughput Screening, Genetic Selection and Fingerprinting. New York. Wiley. 2005

Publicaciones en Revistas

Pérez Cabello, Jesús Á., Silvera , Lucía, Muñoz Franco, Jaime, Capilla González, Vivian, Armaos, Alexandros, et. al.:
MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2023. Vol. 120. Núm. 28. 10.1073/pnas.2302143120

Garcia, Raquel, Martín, Laura, Blanca, Laura, Pérez Cabello, Jesús Á., García García, Raquel:
Review/Reseña: Immune Signaling Kinases in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). En: International Journal of Molecular Sciences. 2021. Vol. 22. Núm. 24. 10.3390/ijms222413280

María M. Leal Lasarte, Mannini, Benedetta, Chiti, Fabrizio, Vendruscolo, Michele, Dobson, Christopher, et. al.:
Distinct responses of human peripheral blood cells to different misfolded protein oligomers. En: Immunology: the journal of cells, molecules, system and technologies. 2021. Vol. 164. Núm. 2. Pag. 358-371. 10.1111/imm.13377

Mannini, Benedetta, Vecchi, Giulia, Labrador Garrido, Adahir, Fabre, B., Fani, Giulia, et. al.:
Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers. En: ACS Chemical Neuroscience. 2019. Vol. 10. Núm. 8. Pag. 3464-3478

Villadiego Luque, Francisco Javier, Labrador Garrido, Adahir, Leal Lasarte, M. Magdalena, Muñoz Franco, Jaime, De Genst, Erwin J., et. al.:
Immunization with alpha-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model. En: Glia. 2018. Vol. 66. Núm. 1. Pag. 191-205. 10.1002/glia.23237

Johnson, Ian P, Roodveldt, Cintia:
Commentary: Immunochemical Markers of the Amyloid Cascade in the Hippocampus in Motor Neuron Diseases. En: Frontiers in Neurology. 2017. 10.3389/fneur.2017.00105

Leal Lasarte, M. Magdalena, Muñoz Franco, Jaime, Labrador Garrido, Adahir, Pozo Pérez, David, Roodveldt, Cintia:
Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia. En: The FASEB Journal. 2017. 10.1096/fj.201601163R

Sot, B, Rubio Muñoz, a, Leal Quintero, a, Martínez Sabaneo, J, Marcela, M, et. al.:
The chaperonin CCT inhibits assembly of alpha-synuclein amyloid fibrils by a specific, conformation-dependent interaction. En: Scientific Reports. 2017. 10.1038/srep40859

Caballero Hernández, Diana, Toscano, Miguel, Cejudo Guillén, Marta, García Martín, María Luisa, Lopez Enriquez, Soledad, et. al.:
Review/Reseña: The 'Omics' of Amyotrophic Lateral Sclerosis. En: Trends in molecular medicine. 2016. Vol. 22. Núm. 1. Pag. 53-67. 10.1016/j.molmed.2015.11.001

Labrador Garrido, Adahir, Cejudo Guillén, Marta, Daturpalli, Soumya, Leal, Maria M, Klippstein Martín, Rebecca, et. al.:
Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the a-synuclein¿elicited immune response. En: The FASEB Journal. 2016. Vol. 30. Núm. 2. Pag. 564-577. 10.1096/fj.15-275131

Chen, Sw, Drakulic, S, Deas, e, Roodveldt, Cintia, Valpuesta, Jm, et. al.:
Structural characterization of toxic oligomers that are kinetically trapped during ¿-synuclein fibril formation. 2015. Vol. 112. Núm. 16. 10.1073/pnas.1421204112

Chen, Sw, Drakulic, S, Roodveldt, Cintia, Valpuesta, Jm, Dobson, Cm, et. al.:
Structural characterization of toxic oligomers that are kinetically trapped during ¿-synuclein fibril formation. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2015. 10.1073/pnas.1421204112

Labrador Garrido, Adahir, Cejudo Guillén, Marta, Klippstein Martín, Rebecca, De Genst, Erwin, Tomás Gallardo, Laura, et. al.:
Chaperoned amyloid proteins for immune manipulation: a-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype. 2015. Vol. 2. Núm. 4. Pag. 226-238. 10.1002/iid3.39

Labrador Garrido, Adahir, Cejudo Guillén, Marta, Klippstein Martín, Rebecca, De Genst, Erwin J, Tomás Gallardo, Laura, et. al.:
Chaperoned amyloid proteins for immune manipulation: a-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype. En: Immunity, Inflammation & Disease. 2014. Vol. 2. Núm. 4. Pag. 226-238. 10.1002/iid3.39

Tomás Gallardo, Laura, Labrador Garrido, Adahir, Cejudo Guillen, Marta, Klippstein, Rebecca, De Genst, Erwin J, et. al.:
Chaperoned amyloid proteins for immune manipulation: alpha-synuclein/Hsp70 shifts immunity towards a modulatory phenotype. En: Immunity, Inflammation & Disease. 2014. 10.1002/iid3.39

Roodveldt, Cintia, Labrador Garrido, Adahir, Fernández Montesinos, Rafael, Lachaud, Christian C, Guilliams, Tim, et. al.:
Preconditioning of microglia by alpha-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation. En: PLoS One. 2013. Vol. 8. Núm. 11

Aprile, Francesco a, Dhulesia, Anne, Stengel, Florian, Roodveldt, Cintia, Benesch, Justin L, et. al.:
Hsp70 Oligomerization Is Mediated By An Interaction Between The Interdomain Linker And The Helical Lid Of The Substrate-Binding Domain. En: PLoS One. 2013. Vol. 8. Núm. 6

Roodveldt, Cintia, Andersson, August, De Genst, Erwin J., Labrador Garrido, Adahir, Buell, Alex K., et. al.:
A Rationally Designed Six-Residue Swap Generates Comparability in the Aggregation Behavior of ¿-Synuclein and ß-Synuclein. En: Biochemistry-US. 2012. Vol. 51. Núm. 44. Pag. 8771-8778

Mannini, Benedetta, Cascella, R., Zampagni, M., Van Waarde Verhagen, M., Meehan, Sarah, et. al.:
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2012. Vol. 109. Núm. 31. Pag. 12479-12484

Roodveldt, Cintia, Labrador Garrido, Adahir, Gonzalez Rey, Elena, Caro, Marta, Fernández Montesinos, Rafael, et. al.:
Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and parkinson¿s disease-linked mutants. En: PLoS One. 2010. Vol. 5. Núm. 10

Roodveldt, Cintia, Bertoncini, Cw, Andersson, a, Van der Goot, At, Hsu, S.T., et. al.:
Chaperone Proteostasis in Parkinson's Disease: Stabilization of the Hsp70/Alpha-Synuclein Complex by Hip. En: EMBO Journal. 2009. Vol. 28. Pag. 3758-3770

Roodveldt, Cintia, Christodoulou, J, Dobson, Cm:
Review/Reseña: Immunological Features of Alpha-Synuclein in Parkinson's Disease. En: Journal of Cellular and Molecular Medicine. 2008. Vol. 12. Núm. 5B. Pag. 1820-1829

Afriat, L, Roodveldt, Cintia, Manco, G, Tawfik, Ds:
The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase. En: Biochemistry (Moscow). 2006. Vol. 45. Núm. 46. Pag. 13677-13686

Khersonsky, o, Roodveldt, Cintia, Tawfik, Ds:
Review/Reseña: ENZYMe PROMISCUITY: EVOLUTIONARY AND MECHANISTIC ASPECTs. En: Current Opinion in Chemical Biology. 2006. Vol. 10. Pag. 498-508

Aharoni, a, Roodveldt, Cintia, Tawfik, Ds:
Review/Reseña: Directed Evolution for High Expression and Stability of Heterologous Proteins. En: Current Opinion in Structural Biology. 2005. Pag. 50-56

Aharoni, a, Gaidukov, L, Khersonsky, o, Mcq Gould, S, Roodveldt, Cintia, et. al.:
The 'evolvability' of Promiscuous Protein Functions. En: Nature Genetics. 2005. Pag. 73-76

Roodveldt, Cintia, Tawfik, Ds:
Directed Evolution of Phosphotriesterase from Pseudomonas Diminuta for Over-Expression in E. Coli Results in Stabilization of the Metal-Free State. En: Protein Engineering Design & Selection. 2005. Pag. 51-58

Roodveldt, Cintia, Tawfik, Ds:
Shared Promiscuous Activities and Evolutionary Features in Various Members of the Amidohydrolase Superfamily. En: Biochemistry (Moscow). 2005. Pag. 12728-12736

Marcipar, is, Roodveldt, Cintia, Corradi, G, Cabeza, Ml, Brito, Me, et. al.:
Improvement of Trypanosoma Cruzi Diagnosis Routine for Chagas' Disease by Using the Full-Length Recombinant Calflagin and Its C-Fragment. En: Journal of Clinical Microbiology. 2005. Pag. 5498-5503

Marcipar, is, Welchen, e, Roodveldt, Cintia, Marcipar, Aj, Silber, Am:
Purification of the 67-Kda Lectin-Like Glycoprotein of Trypanosoma Cruzi, Llgp-67, and Its Evaluation As a Relevant Antigen for the Diagnosis of Human Infection. En: Fems Microbiology Letters. 2003. Vol. 220. Pag. 149-154

Silber, Am, Marcipar, is, Roodveldt, Cintia, Cabeza Meckert, P, Laguens, R, et. al.:
Trypanosoma Cruzi: Identification of a Galactose-Binding Protein That Binds to Cell Surface of Human Erythrocytes and is Involved in Cell Invasion by the Parasite. En: Experimental Parasitology. 2002. Pag. 217-225

Roodveldt, Cintia:
Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers

Aportaciones a Congresos

Gómez Navas, Carlos, Silvera , Lucía, Garcia, Raquel, Tejada, Daniel, Rafii-el-Idrissi Benhnia, Mohammed, et. al.:
Psma/Gcpii Expression in B Cells: an Unexpected Mechanism Linking Neurotransmitters Metabolism and Immune Function. Poster en Congreso. III CABIMER International Workshop. Cabimer - Centro Andaluz de Biología Molecular y Medicina Regenerativa. 2024

Garcia, Raquel, Silvera , Lucía, Tebaldi, Enrico, Rodríguez Martín, Araceli, Tejada, Daniel, et. al.:
Uncovering MOK kinase as an emerging player in microglial responses through the TBK1/Type-I IFN pathway and mitochondrial function. Poster en Congreso. III CABIMER International Workshop ¿New Frontiers in Metabolism: From Cell to Systems Biology¿. Sevilla. 2024

Silvera , Lucía, Garcia, Raquel, Pérez Cabello, Jesús Á., Tejada, Daniel, Sola, Alejandro, et. al.:
Functional characterization of the ADNP protein (Activity-Dependent Neuroprotective Protein) chromatin modifier uncovers a physiological role of ADNP as a homeostatic repressor in microglia linked to neurodegeneration. Poster en Congreso. III CABIMER International Workshop ¿New Frontiers in Metabolism: From Cell to Systems Biology¿. Sevilla. 2024

Silvera , Lucía, Garcia, Raquel, Cejudo Guillén, Marta, Pérez Cabello, Jesús Á., Sola, Alejandro, et. al.:
Molecular and cellular insights into VIP/ADNP neuropeptide regulation of ALS progression. Poster en Congreso. Gordon Research Conference (GRC) in 'ALS and Related Motor Diseases. Les Diablerets, Suiza. 2023

Silvera , Lucía, Garcia, Raquel, Pérez Cabello, Jesús Á., Sola, Alejandro, Martín Montalvo Sánchez, Alejandro, et. al.:
Gene editing reveals ADNP protein (Activity-Dependent Neuroprotective Protein) physiological roles in microglia and its potential implications in neurodegeneration. Poster en Congreso. European Network to Cure ALS ¿ ENCALS meeting. Barcelona, España. 2023

Garcia, Raquel, Silvera , Lucía, Tebaldi, Enrico, Rodríguez Martín, Araceli, Tejada Moreno, Daniel, et. al.:
Role of MOK kinase in microglial TBK1/type-1 IFN pathway and mitochondrial function. Poster en Congreso. ENCALS Annual Meeting. . Barcelona. 2023

Pérez Cabello, Jesús Á., Silvera , Lucía, Muñoz Franco, Jaime, Capilla González, Vivian, Armaos, Alexandros, et. al.:
MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS. Poster en Congreso. Amyotrophic Lateral Sclerosis (ALS) & Motor Neuron Disease. LEs Diablerets (Suiza). 2023

Pérez Cabello, Jesús Á., Silvera , Lucía, Garcia, Raquel, Gomez, Maria, Armaos, Alexandros, et. al.:
Cell signaling and gene expression regulation in microglia under TDP-43 aggregation. Poster en Congreso. Protein Homeostasis in Health & Disease, Cold Spring Harbor Laboratory. Cold Spring Harbor, - NEW YORK - ESTADOS UNIDOS, EEUU. 2022

Roodveldt, Cintia:
Neurodegenerative proteinopathies: implications and molecular mechanisms of MOK signaling kinase in neuroinflammatory responses. Conferencias impartidas en Seminario. BIFI Talk. Online. 2021

Gómez Lima, M., María M. Leal Lasarte, Muñoz Franco, Jaime, González Sánchez, Zaira Isabel, Armaos, A., et. al.:
Implications of MOK protein kinase in neuroinflammation linked to ALS. Poster en Congreso. Gordon Research Conference (GRC) on `Amyotrophic Lateral Sclerosis (ALS) and Related Motor Neuron Diseases¿. Mt. Snow, VT, EE.UU. 2019

Gómez Lima, M., María M. Leal Lasarte, Muñoz Franco, Jaime, González Sánchez, Zaira Isabel, Armaos, A., et. al.:
A role for MOK protein kinase in neuroinflammation linked to amyotrophic lateral sclerosis. Poster en Congreso. EMBO Workshop on "ProteinQuality Control: from Mechanisms to Disease". Costa de la Calma (Mallorca). 2019

Pozo Pérez, David, Roodveldt, Cintia, María M. Leal Lasarte, González Sánchez, Zaira Isabel, Caballero Hernández, Diana Elia, et. al.:
New insights into the role of innate immune regulation and altered metabolic homeostasis in amyotrophic lateral sclerosis (ALS): Implications for treatment and disease management. Comunicación en congreso. XV Congreso Internacional De Investigacio¿n Cienti¿fica. Santo Domingo. 2019

Roodveldt, Cintia:
Protein aggregation and neuroinflammation in neurodegenerative misfolding disease. Conferencias impartidas en Congreso. EMBO Conference on `Protein Quality Control: From Mechanisms to Disease¿. Tramontana, España. 2019

Roodveldt, Cintia:
TDP-43 misfolding and neuroinflammation in ALS. Conferencias impartidas en Congreso. V International Conference of the Centre for Misfolding Diseases. Trasmina, - Bolonia, Italia. 2018

Labrador Garrido, Adahir, Villadiego Luque, Francisco Javier, De Genst, Erwin J., Dobson, Christopher M., Pozo Pérez, David, et. al.:
Vaccination with alpha-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic model of Parkinson¿s disease. Poster en Congreso. Alpha-synuclein and Parkinson¿s Disease Conference: Lessons from the past 20 years. Barcelona, España. 2017

Roodveldt, Cintia:
Chaperones and immunity in protein misfolding diseases. Conferencias impartidas en Congreso. IV International Conference of the Centre for Misfolding Diseases. Sevilla, España. 2016

Mannini, Bendita, Labrador Garrido, Adahir, Vecchi, Giulia, Fabre, B, Pozo Pérez, David, et. al.:
Immune response triggered by aberrant protein oligomers in microglial cells. Poster en Congreso. Cold Spring Harbor Laboratory Meetings on `Protein Homeostasis in Health and Disease¿. Cold Spring Harbor, EE.UU. 2016

Leal Lasarte, M. Magdalena, Labrador Garrido, Adahir, Pozo, David, Roodveldt, Cintia:
Exogenous TDP-43 species are internalized by microglia and elicit different immune profiles dependent on co-stimulating molecules. Poster en Congreso. Cold Spring Harbor Laboratory Meetings on `Protein Homeostasis in Health and Disease¿. Cold Spring Harbor, EE.UU. 2016

Roodveldt, Cintia:
Vaccination with a Grp94/alpha-synuclein combination as a novel approach for immunotherapy against Parkinson¿s disease. Poster en Congreso. Cold Spring Harbor Laboratory Meetings on `Protein Homeostasis in Health and Disease¿. Cold Spring Harbor, EE.UU. 2016

Roodveldt, Cintia:
Immunization with heat-shock protein-`chaperoned¿ ¿-synuclein as a novel immunotherapeutic strategy against Parkinson¿s Disease. Conferencias impartidas en Congreso. International Congress on Neuroimmunology & Therapeutics. California, California, San Francisco, USA. 2016

Roodveldt, Cintia:
Molecular chaperones and immunity in neurodegenerative proteinopathies. Sesión plenaria en Congreso. Chaperones in the Maintenance of Cellular Proteostasis. - Baeza (Jaén), España. 2016

Roodveldt, Cintia:
Molecular chaperones and immunity in neurodegenerative proteinopathies. Sesión plenaria en Congreso. Chaperones in the Maintenance of Cellular Proteostasis. - Baeza (Jaén), España. 2016

Roodveldt, Cintia:
Molecular chaperones and immunity in neurodegenerative proteinopathies. Sesión no plenaria en Congreso. Chaperones in the Maintenance of Cellular Proteostasis. - Baeza (Jaén), España. 2016

Roodveldt, Cintia:
Chaperones and immunity in protein misfolding diseases. Conferencias impartidas en Congreso. IV International Conference of the Centre for Misfolding Diseases. Sevilla. 2016

Mannini, Bendetta, Labrador Garrido, Adahir, Leal, Maria M, Cejudo Guillen, Marta, Chiti, Fabrizio, et. al.:
¿Immune response triggered by aberrant protein oligomers in microglial cells¿. Poster en Congreso. EMBL Conference `Microglia: guardian of the brain¿. Heidelberg, Germany. 2014

Roodveldt, Cintia, Labrador Garrido, Adahir, Gonzalez Rey, Elena, Lachaud, Christian, Guilliams, Tim, et. al.:
Preconditioning of microglia with Parkinson-linked alpha-synuclein affects the response induced by Toll-like receptor (TLR) stimulation. Poster en Congreso. 11th International Congress of Neuroimmunology. Boston, MA (USA). 2012

Roodveldt, Cintia, Labrador Garrido, Adahir, Gonzalez Rey, Elena, Caro, Marta, Lachaud, Christian, et. al.:
Glial Innate Immunity Generated by Non-Aggregated Alpha-Synuclein: Differences Between Wild-Type and Parkinson Disease-Linked Mutants. Poster en Congreso. 10th International Congress of Neuroimmunology . 2010. Journal of Neuroimmunology. 435. 436

Roodveldt, Cintia:
Alpha-Synuclein Aggregation and the Molecular Origins of Parkinson's Disease. Conferencias impartidas en Congreso. Estudiantes de Postgrado y Personal Cientifico-Investigador. Facultad de Medicina, Universidad de Cadiz. 2009

Labrador Garrido, Adahir, Roodveldt, Cintia:
Differential Modulation of the Neuroinflammatory Response by Wild-Type and Mutant Alpha-Synuclein. Poster en Congreso. Young Scientist Forum Febs. Prague. 2009

Roodveldt, Cintia:
Hsp70, Alpha-Synuclein, and the Molecular Origins of Parkinson's Disease. Conferencia Congreso no publicada. Guest Seminars - Centro Nacional de Biotecnología. Centro Nacional de Biotecnología (Cnb), Madrid. 2009

Labrador Garrido, Adahir, Fernández Montesinos, Rafael, Gonzalez Rey, Elena, Delgado Mora, Mario, Pozo Pérez, David, et. al.:
Modulation of the Innate Response by Alpha-Synuclein and Related Mutants: Characterization of Chemokines, Proinflammatory and Regulatory Cytokines. Poster en Congreso. XXXII Congreso de la Sociedad Española de Bioquímica y Biología Molecular. Oviedo, España. 2009. XXXII Congreso de la Sociedad Española de Bioquímica y Biología Molecular. 227. 227

Roodveldt, Cintia, Bertoncini, Cw., Andersson, A., Van der Goot, A.T., Nollen, E.A.A., et. al.:
Molecular Mechanisms in Parkinson's Disease: the Hsp70/Alpha-Synuclein Crosstalk. Poster en Congreso. XXXII Congreso de la Sociedad Española de Bioquímica y Biología Molecular. Oviedo, España. 2009. XXXII Congreso de la Sociedad Española de Bioquímica y Biología Molecular. 227. 227

Labrador Garrido, Adahir, Fernández Montesinos, Rafael, Gonzalez Rey, Elena, Delgado, M, Pozo Pérez, David, et. al.:
Differential Modulation of the Neuroinflammatory Response by Wild-Type and Mutant Alpha-Synuclein. Comunicación en congreso. Febs Young Scientists Forum. Praga, Repùblica Checa. 2009. Febs Young Scientists Forum 2009. 16. 16

Roodveldt, Cintia:
Parkinson's Disease: Mechanism of Hsp70 Inhibition of Alpha-Synuclein Amyloid Formation. Conferencias impartidas en Congreso. Estudiantes de Postgrado y Personal Cientifico-Investigador. Instituto de Parasitologia y Biomedicina "Lopez Neyra" (Ipbln), (CSIC), Granada, España. 2008

Roodveldt, Cintia:
Hsp70 and Synuclein Intereactions: New Insights Into the Molecular Origin of Parkinson's Disease. Conferencias impartidas en Congreso. Estudiantes de Postgrado y Personal Cientifico-Investigador. Facultad de Bioquimica Medica y Biologia Molecular, Universidad de Sevilla, España. 2008

Roodveldt, Cintia, Christodoulou, J, Dobson, Cm:
Mechanism of the Hsp70¿S Inhibition of Alpha-Synuclein Fibrillation. Poster en Congreso. Febs Annual Meeting. Viena, Austria. 2007. febs j. 262. 262

Roodveldt, Cintia, Andersson, a, Bertoncini, Cw, Christodoulou, J, Pozo Pérez, David, et. al.:
Molecular Insights Into the Anti-Aggregation Activity of Hsp70 With Alpha-Synuclein. Poster en Congreso. Embo Workshop on Protein Folding and Chaperones. 2007. Embo Workshop on Protein Folding and Chaperones. 14. 14

Roodveldt, Cintia:
How Enzymes Acquire New Functions: Learning from Directed Evolution. Conferencias impartidas en Congreso. Estudiantes de Postgrado y Personal Cientifico-Investigador. Palacio de Congresos y Exposiciones, Granada, España. 2006

Roodveldt, Cintia, Tawfik, Ds:
Evolution of the Promiscuous Activities in Members of the Amidohydrolase Superfamily of Enzymes. Poster en Congreso. Gordon Research Conference. Meriden (Nh), EEUU. 2004

Roodveldt, Cintia:
Mi experiencia como 'investigadora móvil'. Conferencias impartidas en Congreso

Roodveldt, Cintia:
Docencia impartida- BIOQUIMICA Y BIOLOGIA MOLECULAR BASICA, Universidad de Sevilla. Conferencias impartidas en Congreso. Estudiantes de Postgrado y Personal Cientifico-Investigador

Patentes:

Roodveldt, Cintia, Leal Lasarte, M. Magdalena, Muñoz Franco, Jaime, Pozo Pérez, David:
Agentes moduladores de MOK para el tratamiento de enfermedades con componente inflamatorio, enfermedades neurodegenerativas, enfermedades inflamatorias y cáncer. Patente de invención, Propiedad industrial. Solicitud: 2017-03-21

Roodveldt, Cintia, Márquez Infante, Celedonio, Pozo Pérez, David, Cejudo Guillén, Marta, Lopez Enriquez, Soledad:
Biomarcadores para la Esclerosis Lateral Amiotrófica (ELA). Patente de invención, Propiedad industrial. Solicitud: 2015-09-15

Roodveldt, Cintia, Labrador Garrido, Adahir, Pozo, David:
`Combinaciones de proteínas agregantes y chaperonas moleculares para el tratamiento de proteinopatías o enfermedades conformacionales¿. Patente de invención, Propiedad industrial. Solicitud: 2013-09-11

Tesis dirigidas y co-dirigidas:

(Doctorando no grabado)
Novel molecular mechanisms and signaling pathways of microglial responses in amyotrophic lateral sclerosis (ALS). Tesis Doctoral. 2018

(Doctorando no grabado)
Alpha-Synuclein and Immune System Crosstalk in Parkinson¿s Disease: Therapeutic approaches of its Modulation by Molecular Chaperones. Tesis Doctoral. 2017

(Doctorando no grabado)
Crosstalk between peripheral and central immunity in amyotrophic lateral sclerosis (ALS). Tesis Doctoral. 2016